Testosterone, social and sexual behavior of perinatally and lifelong calorie restricted offspring

The reduction in sexual behavior induced by neonatal immune stress is not related to androgen levels in male rats

“…Two weeks later, estradiol benzoate (10 μg/body) dissolved in 0.1 mL sesame oil was injected subcutaneously (s.c.) into the backs of the female rats at 48 h and 24 h before the test session. Progesterone (1 mg/body) dissolved in 0.2 mL sesame oil was injected s.c. into the female rats 4 h before the test session (Govic et al, 2008; matsuzaki et al, 2017). At 11 and 12 weeks of age, sexual behavior tests were conducted under the following conditions.…”

Prenatal undernutrition disrupted the sexual maturation, but not the sexual behavior, in male rats

“…At 2 weeks after the ovariectomy, the rats were subcutaneously injected with estradiol benzoate (10 μg in 0.1 mL peanut oil; Sigma, St. Louis, MO, USA), followed 48 hours later with progesterone (1 mg in 0.1 mL peanut oil; Sigma). The sexual behavior was checked 4 hours after the progesterone injection . The sexual behavior of the male rats was tested at 11 weeks of age under the following condition: an experimental male rat and a partner female rat were placed one‐by‐one in an acrylic cage (70 cm × 45 cm × 34 cm).…”

Impact of androgen deprivation therapy on sexual function

“…42 Nevertheless, this equilibrium is fragile and some studies have shown that the environment can also impact on it. Indeed, some stressors such as food restriction, [43][44][45] sleep deprivation [35][36][37][38][39] and exposure to the radiofrequency emitted by a conventional mobile phone 46,47 have been shown to be able to cause a stress sufficient enough to disturb it.…”