Testing pulmonary physiology in ventilated non‐human primates
Orlando Cervantes,
Melissa R. Berg,
Siddhartha G. Kapnadak
et al.
Abstract:BackgroundAnimal models of respiratory viral infections are essential for investigating disease pathogenesis and the efficacy of antivirals and vaccine candidates. A major limitation in the research of respiratory diseases in animal models is correlating clinically relevant changes in pulmonary physiology with cellular and molecular mechanistic studies. Few animal models have captured and correlated physiologic changes in lung function and immune response within same experiment, which is critical given the het… Show more
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