Testing of potential biomarkers of cerebral ischemia and vasospasm in patients with cerebral aneurysm surgery
Abstract:Biomarkers for the prediction of vasospasm and delayed cerebral ischemia in patients with a ruptured cerebral aneurysm could be helpful.In this prospective clinical study, endothelin-1, lactate, pCO 2 , and pO 2 were measured in arterial and internal jugular vein blood before, during and after surgical treatment of a cerebral aneurysm, and were tested as potential predictors of neurologic outcome in patients.Forty-one patients were enrolled in the study, 23 of them were operated on after aneurismal rupture wit… Show more
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