Testing of neuroendocrine function in astronauts as related to fluid shifts

Sauseng-Fellegger, G.; König, E; Hinghofer‐Szalkay, Helmut; Ježová, Daniela; Vigaŝ, M

doi:10.1016/0094-5765(92)90176-j

Cited by 2 publications

(1 citation statement)

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“…Hormonal response to exercise depends on exogenous conditions such as exercise type and intensity; ambient temperature and humidity, and daytime as well as on endogenous factors, for example, muscle mass and inherited disposition, physical fitness, and type of training performed previously 1‐9. Severe reduction of physical activity is followed by deconditioning also modifying the endocrine responses to physical exercise 10‐13.…”

Section: Introductionmentioning

confidence: 99%

Effects of Endurance Training on Endocrine Response to Physical Exercise after 5 Days of Bed Rest in Healthy Male Subjects

Koška¹,

Kšinantová²,

Květňanský³

et al. 2004

Annals of the New York Academy of Sciences

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The study was designed to evaluate how a bout of endurance training (ET) influences the endocrine response after head-down bed rest (HDBR). Eleven healthy males completed the study, which consisted of a 6-wk ET followed by 5 days of -6 degrees head-down HDBR. Treadmill exercise at 80% of pretraining maximal aerobic capacity (VO(2max)) was performed before and after ET as well as after HDBR. ET increased VO(2max) by 13%. The response of norepinephrine was attenuated after ET and exaggerated after HDBR (P < 0.001). The differences in epinephrine responses were not statistically significant. The responses of cortisol and plasma renin activity (PRA) were unchanged after ET and were enhanced after HDBR (P < 0.001). The response of growth hormone after HDBR was reduced (P < 0.05). Only the change in cortisol response was associated with the increment of VO(2max) after ET (r = 0.68, P < 0.01). Endurance training failed to completely prevent changes in endocrine responses seen after HDBR. Improvement of physical fitness was associated with an enhancement of the cortisol response to exercise following the period of bed rest.

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Section: Introductionmentioning

confidence: 99%