“…The dependency of certain tumours on hormonal factors as well as the association of various types of cancer with abnormal endocrine environment has been observed by numerous workers (Noble, 1964;Sinha, 1966;Karande and Ranadive, 1966;Takakura et al, 1967;Pai and Ranadive, 1971). There are also several reports on the inhibitory effect and therapeutic application of steroid hormones on different types of cancer (Kelley and Baker, 1961 ;Segaloff, 1964;Dorfman, 1965).…”