Testing for SARS-CoV-2: Can We Stop at 2?

Lee, Tau Hong; Lin, Ray Junhao; Lin, Raymond Tzer Pin; Barkham, Timothy; Rao, Pooja; Leo, Yee‐Sin; Lye, David C.; Young, Barnaby Edward

doi:10.1093/cid/ciaa459

Cited by 58 publications

(53 citation statements)

References 6 publications

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“…19 The requirement for 2 tests 24 hours apart was supported by local studies demonstrating increased testing yield due to the possibility of intermittent viral shedding or variations in sampling technique. 20 For patients admitted into the RSW with a primary nonrespiratory condition who concomitantly had URTI, SARS-CoV-2 testing was performed if the patient was to be transferred from the designated wards, with the caveat that testing should only be done at day 5 of symptoms. This procedure was supported by local studies that obtained good testing yield when sampling patients presenting with a median of 5 days of symptoms.…”

Section: Respiratory Surveillance Wards (Rsws): Admissions Criteria mentioning

confidence: 99%

“…This procedure was supported by local studies that obtained good testing yield when sampling patients presenting with a median of 5 days of symptoms. 20 Additionally, because patients with URTI symptoms were generally more well, this approach conserved testing resources in the initial phase of the outbreak. From March 1 onward, all patients with URTI alone had 1 swab done on admission, followed by the second swab on day 5 of symptom onset.…”

Section: Respiratory Surveillance Wards (Rsws): Admissions Criteria mentioning

confidence: 99%

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Respiratory surveillance wards as a strategy to reduce nosocomial transmission of COVID-19 through early detection: The experience of a tertiary-care hospital in Singapore

Wee

Hsieh

Phua

et al. 2020

Infect. Control Hosp. Epidemiol.

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Objectives: Patients with COVID-19 may present with respiratory syndromes indistinguishable from those caused by common viruses. Early isolation and containment is challenging. Although screening all patients with respiratory symptoms for COVID-19 has been recommended, the practicality of such an effort has yet to be assessed.Methods: Over a 6-week period during a SARS-CoV-2 outbreak, our institution introduced a "respiratory surveillance ward" (RSW) to segregate all patients with respiratory symptoms in designated areas, where appropriate personal protective equipment (PPE) could be utilized until SARS-CoV-2 testing was done. Patients could be transferred when SARS-CoV-2 tests were negative on 2 consecutive occasions, 24 hours apart.

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Section: Respiratory Surveillance Wards (Rsws): Admissions Criteria mentioning

confidence: 99%

Section: Respiratory Surveillance Wards (Rsws): Admissions Criteria mentioning

confidence: 99%

Respiratory surveillance wards as a strategy to reduce nosocomial transmission of COVID-19 through early detection: The experience of a tertiary-care hospital in Singapore

Wee

Hsieh

Phua

et al. 2020

Infect. Control Hosp. Epidemiol.

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“…All admitted suspect cases received an initial chest x‐ray and were tested for SARS‐CoV‐2 by means of RT‐PCR from respiratory specimens over two consecutive days . Clinicians were given the liberty to perform additional tests based on clinical or epidemiological grounds.…”

Section: Singapore's Covid‐19 Responsementioning

confidence: 99%

FromSARStoCOVID‐19: the Singapore journey

Lin

Lee

Lye

2020

Medical Journal of Australia

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“…Initial NP RT-PCR testing is more sensitive than OP testing in both severe (73.3% versus 60.0%) and mild (72.1% versus 61.3%) COVID-19 cases [29]. A separate study demonstrated improvement in NT-PCR sensitivity (from 88.6%-95.7%) when repeated after 24 hours in patients who initially tested negative [30]. Thus, NP RT-PCR is the current recommended investigation [31].…”

Section: Preoperative Testingmentioning

confidence: 99%

Addressing Coronavirus Disease 2019 in Spine Surgery: A Rapid National Consensus Using the Delphi Method via Teleconference

et al. 2020

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The magnitude and potential duration of the current coronavirus disease 2019 pandemic is something that most doctors currently in practice have yet to experience. While considerable information regarding COVID-19 is being published every day, it is challenging to filter out the most relevant or appropriate information for our individual practice. The Spine Society of Singapore convened via a teleconference on April 24, 2020 to collaborate on a national level and share collective wisdom in order to tackle the ongoing crisis. In the teleconference, 13 spine surgeons from across various hospitals in Singapore constituted the panel of experts.The following topics were discussed: repurposing of surgeons, continuity of spine services, introduction of telemedicine, triaging of spinal surgeries, preoperative testing, new challenges in performing spine surgery, and preparing for the post-pandemic era. While some issues required only the sharing of best practices, the Delphi panel method was adopted to form a consensus on others. Existing spine specific triage guidelines were debated and a locally accepted set of guidelines was established. Although preoperative testing is currently not performed routinely, the panel voted in favor of its implementation because they concluded that it is vital to protect themselves, their colleagues, and their patients. Solutions to operating room specific concerns were also discussed. This article reflects the opinions and insights shared during this meeting and reviews the evidence relevant to the issues that were raised. The rapid consensus reached during the teleconference has enabled us to be concerted, and thus stronger, in our national efforts to provide the best standard of care via our spine services in these challenging times. We believe that this article will provide some guidance for addressing COVID-19 in spine surgery and encourage other national/regional societies to conduct similar discussions that would help their navigation of this pandemic.

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Testing for SARS-CoV-2: Can We Stop at 2?

Abstract: The COVID-19 epidemic requires accurate identification and isolation of confirmed cases for effective control. This report describes the effectiveness of our testing strategy and highlights the importance of repeat testing in suspected cases in our cohort.

Cited by 58 publications

References 6 publications

Respiratory surveillance wards as a strategy to reduce nosocomial transmission of COVID-19 through early detection: The experience of a tertiary-care hospital in Singapore

Respiratory surveillance wards as a strategy to reduce nosocomial transmission of COVID-19 through early detection: The experience of a tertiary-care hospital in Singapore

FromSARStoCOVID‐19: the Singapore journey

Addressing Coronavirus Disease 2019 in Spine Surgery: A Rapid National Consensus Using the Delphi Method via Teleconference

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