Testing for neglect in right-hemispheric stroke patients using a new assessment battery based upon standardized activities of daily living (ADL)

Eschenbeck, Philipp; Vossel, Simone; Weiss, Peter H.; Saliger, Jochen; Karbe, H.; Fink, Gereon R.

doi:10.1016/j.neuropsychologia.2010.07.034

Cited by 31 publications

(22 citation statements)

References 45 publications

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“…The sample was then categorized according to the presence of neglect in the computerized test (54%), in the standard tests (20%), and in the occupational therapy test (28%). In other words, the light detection task resulted to be more sensitive than the standard clinical measures (see also Beis et al, 1994; Eschenbeck et al, 2010). …”

Section: Computer-based Testing and Increased Task Demands Results In mentioning

confidence: 99%

“…To our knowledge only a few studies (e.g., Deouell et al, 2005; Hasegawa et al, 2011) described in detail the impairments shown by chronic patients without neglect according to paper-and-pencil tests in complex, truly ecological, everyday settings. The main disadvantage of the FIM, Barthel and Bergego scales is that the resulting scores only allow quantifying disability in easy tasks such as eating or dressing, but do not appear to be precise enough to detect subtle neglect in complex everyday life activities, and lack scores related to dual-task performance (but see Eschenbeck et al, 2010 for a more sensitive neglect-related ADL assessment). Additionally, they do not clarify whether contralesional performance is impaired because of motor or attentional deficits when patients, as commonly occurs, have concurrent motor deficits.…”

Section: Computer-based Testing and Increased Task Demands Results In mentioning

confidence: 99%

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Neglect and Extinction Depend Greatly on Task Demands: A Review

Bonato

2012

Front. Hum. Neurosci.

125

124

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This review illustrates how, after unilateral brain damage, the presence and severity of spatial awareness deficits for the contralesional hemispace depend greatly on the quantity of attentional resources available for performance. After a brief description of neglect and extinction, different frameworks accounting for spatial and non-spatial attentional processes will be outlined. The central part of the review describes how the performance of brain-damaged patients is negatively affected by increased task demands, which can result in the emergence of severe awareness deficits for contralesional space even in patients who perform normally on paper-and-pencil tests. Throughout the review neglect is described as a spatial syndrome that can be exacerbated in the presence and severity by both spatial and non-spatial tasks. The take-home message is that the presence and degree of contralesional neglect and extinction can be dramatically overlooked based on standard clinical (paper-and-pencil) testing, where patients can easily compensate for their deficits. Only tasks where compensation is made impossible represent an appropriate approach to detect these disabling contralesional deficits of awareness when they become subtle in post-acute stroke phases.

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Section: Computer-based Testing and Increased Task Demands Results In mentioning

confidence: 99%

Section: Computer-based Testing and Increased Task Demands Results In mentioning

confidence: 99%

Neglect and Extinction Depend Greatly on Task Demands: A Review

Bonato

2012

Front. Hum. Neurosci.

125

124

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“…The remaining 56 subjects were patients who had suffered from a right-hemispheric stroke (58.2±1.1 years, 18 females, mean time poststroke±SEM: 112.2±31.8 days). These patients were part of a larger study sample of patients with right-hemispheric stroke 20 21. Patients with left-hemispheric lesions, signs of dementia (Mini Mental State Examination (MMSE22) score <25) or psychiatric disorders including alcohol or drug abuse were excluded from the study.…”

Section: Methodsmentioning

confidence: 99%

Visual extinction in relation to visuospatial neglect after right-hemispheric stroke: quantitative assessment and statistical lesion-symptom mapping

Vossel¹,

Eschenbeck²,

Weiss

et al. 2011

Journal of Neurology, Neurosurgery & Psychiatry

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Background Visual neglect and extinction are two common neurological syndromes in patients with righthemispheric brain damage. Whether and how these two syndromes are associated or share common neural substrates is still a matter of debate. Methods To address these issues, the authors investigated 56 patients with right-hemispheric stroke with a novel diagnostic test to detect extinction and neglect. In this computerised task, subjects had to respond to target stimuli in uni-and bilateral stimulation conditions with detection probabilities being assessed. A cluster-analytical approach identified 18 patients with neglect and 13 patients with extinction. Statistical lesion-symptom mapping analyses with measures for extinction and neglect were performed. Results Extinction and neglect co-occurred in a subset of patients but were also observed independently from each other, thereby constituting a double dissociation. Lesions within the right inferior parietal cortex were significantly associated with the severity of visual extinction. Visuospatial neglect was related to damage of fronto-parietal brain regions, with parieto-occipital areas affecting line bisection and dorsal fronto-parietal areas affecting cancellation task performance, respectively. Conclusion Quantifying lesion-induced symptoms with this novel paradigm shows that extinction and neglect are dissociable syndromes in patients with righthemispheric stroke. Furthermore, extinction and neglect can be related to differential neural substrates, with extinction being related to focal brain damage within the right inferior parietal cortex.

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“…Irrespective of the laterality of the attentional deficit , patients were diagnosed as suffering from spatial inattention if they exhibited a pathological score in at least one of the five attention tests (for similar procedures in patients with RH damage see (Becker & Karnath, 2007;Eschenbeck et al, 2010;Karnath, Rennig, Johannsen, & Rorden, 2011;Ogden, 1985;Robertson et al, 1994). .…”

Section: Neuropsychological Assessmentmentioning

confidence: 99%