Testicular tumors. A clinicopathological study

Dixon, Frank J.; Moore, Robert A.

doi:10.1002/1097-0142(195305)6:3<427::aid-cncr2820060302>3.0.co;2-u

Cited by 309 publications

(58 citation statements)

References 10 publications

(4 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Willis (1953) had one example in 50 testicular tumours. All these authors emphasise the difficulty in differentiating between the interstitial cell and the even rarer adrenal rest tumour, only two of which are described by Dixon and Moore (1953). In a series of 85 testicular tumours reported from this department (Jones, 1955) Baulien, 1954;Forrest and Peebles-Brown, 1955).…”

Section: Resultsmentioning

confidence: 99%

Experimental Production of Interstitial Cell Tumours

Jones¹

1955

Br J Cancer

View full text Add to dashboard Cite

show abstract

Section: Resultsmentioning

confidence: 99%

Experimental Production of Interstitial Cell Tumours

Jones¹

1955

Br J Cancer

View full text Add to dashboard Cite

show abstract

“…Thus, the 2 tumour groups showed opposite tendencies for the cellular and extracellular parameters, and within the same group, the 2 parameters seemed to be inversely correlated. (Dixon & Moore, 1953;Shivas & Douglas, 1972;Howard et al, 1976) possibly by producing acid mucopolysaccharides themselves (Takeuchi et al, 1976;Sampaio et al, 1977;Glimelius et al, 1978). However, strong metachromasia, frequently seen in metastatic tumours, might inhibit cellular responses.…”

Section: Discussionmentioning

confidence: 99%

Local responses in primary and secondary human lung cancers. I. Patterns of cellular (eosinophils and macrophages) and extracellular (acid mucopolysaccharide) reactions

Müller¹,

Kolb²

1979

Br J Cancer

View full text Add to dashboard Cite

Summary.-Local free cell (eosinophils and macrophages) and extracellular (acid mucopolysaccharides) reactions were studied by histochemical techniques in 72 primary lung cancers (Group A), 17 pulmonary metastases and 5 lung tumours of unknown origin (Group B). Strong cellular reactions were more frequent in Group A than in Group B, whereas extracellular reactions were more frequent in Group B than in Group A. In both groups the degrees of eosinophilic infiltration and accumulation of acid mucopolysaccharides tended to be negatively correlated. In contrast, macrophages and eosinophils showed a positive correlation in the primary cancers, but none in the other tumours.The extracellular material had physical and chemical properties (solubility, affinity to stains and degradability by enzymes) of the sulphated acid mucopolysaccharides. From its distribution it appeared to be derived from fibroblasts and/or tumour cells.

show abstract

“…Their observation resulted in embryonal carcinoma being ultimately accepted as a distinctive form of testicular germ cell neoplasia. The AFIP material was utilized again by Dr Frank J Dixon ( Figure 4) (at that time at the University of Pittsburgh and later to become an eminent immunobiologist) and Dr Moore, not only in a publication that appeared in Cancer in 1953 25 with more clinical data than the paper of Friedman and Moore, but also in their first series fascicle published in 1952. 26 The article of Dixon and Moore was preceded by an anonymous one page essay on the history of testicular tumors, 27 possibly by Dixon or Moore or perhaps the editor of Cancer at that time, Dr Fred W Stewart.…”

Section: The Testismentioning

confidence: 99%

A brief history of the pathology of the gonads

Young

2005

Mod Pathol

View full text Add to dashboard Cite

Our understanding of gonadal pathology has reached its current state as a result of the contributions of numerous outstanding investigators. Knowledge of testicular tumor pathology dates back to the great British workers Percival Pott and Sir Astley Cooper but the single greatest early stride was made with the description in 1906 by the French urologist Maurice Chevassu of the seminoma. The seminal 1946 paper of Nathan B Friedman and Robert A Moore, which segregated out as a distinct entity embryonal carcinoma, is, however, the foundation for the current classification of testicular tumors. In that year Pierre Masson described the distinctive neoplasm, the spermatocytic seminoma. The 1950s saw the publication of an important paper by Frank J Dixon and Dr Moore and they also wrote the first series fascicle on testicular tumors. In this same timeframe, and thereafter, Robert E Scully made significant contributions to testicular pathology, writing the first English language paper on spermatocytic seminoma, describing several subtypes of sex cord tumor, and also the distinctive lesion of intersex, the gonadoblastoma, as well as playing a major role in 1980 in formulating the current classification of premalignant lesions of the testis. The current classification of testicular tumors was arrived at in the early 1970s when the World Health Organization, under the leadership of Dr FK Mostofi, who himself made notable contributions to testicular pathology, devised what is fundamentally the current classification of neoplasms of the male gonad. Although comments on ovarian pathology were made by such legendary figures of earlier times as Giovanni Battista Morgagni and Matthew Baillie, it is only in the mid to later years of the 19th century that contributions, mostly in Europe, began to move knowledge of ovarian pathology to its current state. Thomas Hodgkin, Richard Bright, and Sir James Paget all wrote extensively on ovarian neoplasms. In 1870, Heinrich Waldeyer, and later in that century, another German, Hermann Johannes Pfannenstiel wrote important papers on the surface epithelial tumors. The latter was likely the first to refer to neoplasms now known as of 'borderline malignancy' and also wrote on pseudomyxoma peritonei and other topics. Their work was followed by that of Robert Meyer who made monumental contributions to gynecological pathology, including recognizing the Brenner tumor as a distinctive neoplasm and proposing the first classification of Sertoli-Leydig cell tumors (arrhenoblastomas). He also coined the term 'disgerminoma' (soon changed to dysgerminoma) for the ovarian tumor that had been described in detail by the French investigator Marcel Chenot 5 years after Chevassu had mentioned the tumor in his paper describing the seminoma. During the Meyer era other significant contributions were made by, among others, Howard C Taylor writing on the borderline tumors and John A Sampson writing on endometriosis and tumors, associated with it. In the second-half of the 20th century major contributions were made b...

show abstract

Testicular tumors. A clinicopathological study

Cited by 309 publications

References 10 publications

Experimental Production of Interstitial Cell Tumours

Experimental Production of Interstitial Cell Tumours

Local responses in primary and secondary human lung cancers. I. Patterns of cellular (eosinophils and macrophages) and extracellular (acid mucopolysaccharide) reactions

A brief history of the pathology of the gonads

Contact Info

Product

Resources

About