Testicular mixed germ cell tumor in a transgender woman

Fine, Noam; Abbott, Todd; Wintner, Anton

doi:10.1016/j.eucr.2021.101861

Cited by 4 publications

(3 citation statements)

References 4 publications

(5 reference statements)

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“…Transgender individuals face substantial barriers to accessing health care, including healthcare professional bias, lack of general knowledge about best practices, and limited accessibility to gender-affirming surgery [6]. Providers with less exposure to the transgender population have reported lower levels of comfort with discussions regarding gender identity and counseling for required medical care [7]. As there is difficulty in determining the prevalence of reproductive cancers in the transgender population, current guidelines suggest routine screening of retained internal organs.…”

Section: Discussionmentioning

confidence: 99%

Cystic Teratoma Resection With Ovarian Preservation in a Pediatric Transgender Male: A Case Report

Federico¹,

Patel²,

Cummings³

2022

Cureus

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Ovarian teratomas are germ cell-derived tumors that are classically reported in the literature to occur in cisgender female patients. While this is statistically the most common patient population that they are diagnosed in, they can also occur in transgender men with ovaries who have not undergone a previous oophorectomy. Because of the lack of research and literature regarding this unique patient population, decisions regarding the treatment of these neoplasms are controversial. Here, we report the case of a pediatric transgender male who developed an ovarian teratoma and discuss specific considerations for treating ovarian neoplasms in the transgender population.

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Section: Discussionmentioning

confidence: 99%

Cystic Teratoma Resection With Ovarian Preservation in a Pediatric Transgender Male: A Case Report

Federico¹,

Patel²,

Cummings³

2022

Cureus

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“…This is arguably more important for TGD who do not undergo GAS. A sensitive and well informed clinician who develops a strong rapport with transgender patients may be in a unique position to aid in the timely diagnosis of TC in this population [45]. A physician's responsibility may lie in improving their clinical awareness on TC including TGD individuals before GAS who still have testes in situ and so still carry a TC risk, taking a risk factor history, educating the patient on what is normal for them or at least if there are noticeable changes during GAHT (or even without) to present to a specialist for examination.…”

Section: Meyer Et Al [29]mentioning

confidence: 99%

Urologic oncology considerations in transgender and gender diverse patients

Tinajero,

Rashid

2024

Current Opinion in Urology

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Purpose of review This review delves into the pressing issue of urologic oncology considerations within the transgender and gender-diverse (TGD) community. With estimates suggesting that TGD individuals constitute 0.3 to 0.5% of adults worldwide, and this number steadily rising, our review examines the barriers that impede the delivery of excellent quality care, particularly in the context of cancer diagnosis and treatment. Recent findings Recent findings highlight disparities in cancer screening, diagnosis, and treatment access for TGD individuals. These challenges are compounded by a dearth of research and the failure of healthcare systems to account for gender identity and its nuances in data collection. Main themes in the literature include the impact of gender-affirming hormone therapy and surgery on cancer risk, challenges in prostate cancer screening and management, and considerations pertinent to testicular and other urological cancers in TGD patients. Summary The implications for clinical practice and research are profound and emphasize the need for multidisciplinary approaches that cater to the unique healthcare needs of TGD individuals. This includes comprehensive strategies for inclusive and accurate data collection, alongside the development of evidence-based guidelines for cancer screening and management tailored specifically to this population.

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“…She was found to have a 2.5 cm mass on left testicular ultrasound which prompted an expedited radical orchiectomy. Surgical pathology identified a mixed germ cell tumor [20]. Another case describes a 30-year-old transgender woman who presented with a painless mass in her right scrotum confirmed on exam.…”

Section: Testicular Neoplasms In Transgender Women Reported In Litera...mentioning

confidence: 99%

Incidental discovery of seminoma after simple orchiectomy in transgender individuals: A case series

Tausinga,

Snyder,

Mahlow

et al. 2023

J Case Rep Images Urol

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Introduction: Seminoma is a common malignancy reported in young, cisgender men. However, there is sparse literature describing cases of seminoma in the transgender and gender diverse patient population. Case Series: We present two cases of seminoma incidentally discovered after simple bilateral orchiectomy performed as part of genital gender affirming surgery. In both instances, patients had not reported any testicular firmness or abnormality prior to surgery. After a thorough literature review, only two other such cases have been reported. Herein, we discuss our two cases and their implications for surgical management of suspected testicular malignancy intraoperatively, a methodical inspection of testicles removed during gender affirming surgery and providing affirming care when navigating discussions of genitalia with transgender and gender diverse patients. Conclusion: Testicular malignancy such as seminoma may be found incidentally when transgender and gender diverse patients undergo genital gender affirming surgery. Thus, special attention is required to identify suspicious exam findings, adjust surgical techniques as indicated, and properly examine surgical specimens. As there is a significant paucity of literature surrounding testicular malignancies in the transgender and gender diverse patient population, it is crucial to continue to investigate how to provide affirming care in these situations.

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Testicular mixed germ cell tumor in a transgender woman

Cited by 4 publications

References 4 publications

Cystic Teratoma Resection With Ovarian Preservation in a Pediatric Transgender Male: A Case Report

Cystic Teratoma Resection With Ovarian Preservation in a Pediatric Transgender Male: A Case Report

Urologic oncology considerations in transgender and gender diverse patients

Incidental discovery of seminoma after simple orchiectomy in transgender individuals: A case series

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