Testicular metastases from solid tumors: An autopsy study

García-González, Rosa; Pinto, Jesús; Val-Bernal, J. Fernando

doi:10.1016/s1092-9134(00)90012-1

Cited by 55 publications

(45 citation statements)

References 17 publications

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“…In the literature, cases of testicular carcinoma and metastases in the testis are diagnosed mostly in an early stage because of clinical symptoms, such as swelling and pain [9]. In contrast, our patient did not show any clinical symptoms at all and the results of conventional imaging procedures, including sonography, CT and MRI were also negative.…”

Section: Discussioncontrasting

confidence: 58%

“…In agreement with the elevated AFP value the high intensity of the focal uptake in our patient suggested a neoplastic process. Additional diagnostic information by means of F-18-FDG PET cannot be obtained; e. g., primary and secondary malignant processes like meatastases from lung cancer, malignant melanoma, or pancreatic cancer cannot be distinguished [9]. In this case report we wanted to demonstrate that a carcinoma of the testis could be detected in F-18-FDG PET.…”

Section: Discussionmentioning

confidence: 95%

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Diagnosis of a Contralateral Second Testicular Carcinoma by F18-FDG PET

et al. 2003

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Background: In testicular carcinoma the early diagnosis is very important because with an early therapy there are good chances for long-term survival (50–90%). Metastases of a testicular carcinoma are at first lymphogeneous, hematogeneous only in late stages. Case Report: This is a case report about a 28-year-old man, whose testicular carcinoma (left testis) had already been operated on (unripe teratoma with parts of an embryonic carcinoma, an endodermal sinus tumor and a chorion carcinoma). Because of the elevated tumor marker AFP an FDG PET (F18-fluorodeoxyglucose positron emmission tomography) investigation was made. CT (covering thorax, abdomen and pelvis) and ultrasound of the testis showed no pathological results. In the FDG PET a significant pathological FDG uptake in the right testis was found. Histology showed an unripe teratoma with parts of an embryonic carcinoma, an endodermal sinus tumor, and a chorion carcinoma. It was a second carcinoma of the contralateral testis. Conclusion: F18-FDG PET was a sensitive and reliable modality for diagnosis in this patient.

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Section: Discussioncontrasting

confidence: 58%

Section: Discussionmentioning

confidence: 95%

Diagnosis of a Contralateral Second Testicular Carcinoma by F18-FDG PET

et al. 2003

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“…Melanoma is a tumor which is known to widely metastasize, involving organs which are not commonly involved by other tumors [12][13][14] . For example, melanoma accounts for more than 50% of metastases to the gallbladder ( Figure 5) and is the second most common metastasis to the spleen and the third most common to the testicle (Figure 6) [15][16][17][18][19] . In our population, 39% of patients with metastatic disease had metastases to atypical locations and 11.6% of patients had metastases only in atypical locations.…”

Section: Discussionmentioning

confidence: 99%

Melanoma metastases in the abdomen and pelvis: Frequency and patterns of spread

Trout

Rabinowitz²,

Platt³

et al. 2013

WJR

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AIM:To investigate the frequency, typical and atypical locations and patterns of melanoma metastases identifiable by computed tomography (CT) in the abdomen and pelvis. METHODS:We performed a retrospective review of index CT examinations of the abdomen and pelvis in patients with melanoma and recorded all findings suggestive of metastatic disease. RESULTS:Metastases were present on 36% (181/508) of the index examinations and most commonly involved the liver (47%) and pelvic lymph nodes (27%). Lower extremity primaries had the highest rate of metastasis (52%). Ocular and head and neck melanomas have a predilection to metastasize to the liver (hepatic involvement in 70% and 63%, respectively, of patients with metastatic disease) and metastases from lower extremity primaries most commonly involve pelvic lymph nodes (54% of patients with metastatic disease). Metastases to atypical locations were present in 14% of patients and most commonly occurred in the subcutaneous tissue and spleen. Primary tumors of the lower extremity, back and head and neck were most commonly associated with atypical metastases. Pelvic metastases are more common with lower extremity primaries (accounting for 70% of cases with pelvic metastases) but 5% of patients with supraumbilical primaries also had pelvic metastases. CONCLUSION:The distribution of metastatic melanoma in the abdomen and pelvis that we have defined should help guide the interpretation of CT exams in these patients.

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“…Testicular metastases are uncommon; in a recent study (147), only five (0.68%) such lesions were demonstrated in 738 consecutive autopsies of men with known solid malignancies. Metastases usually occur in patients with a known malignancy in an advanced stage, and the most common primary sources are prostate tumors (35%), lung tumors (19%), malignant melanoma (9%), colon tumors (9%), and kidney tumors (7%) (120).…”

Section: Metastases To the Testismentioning

confidence: 94%

Sonography of the Scrotum

Dogra¹,

Gottlieb²,

Oka³

et al. 2003

Radiology

616

555

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Ultrasonography (US) with a high-frequency (7.5-10-MHz) transducer has become the imaging modality of choice for examination of the scrotum. US examination can provide information valuable for the differential diagnosis of a variety of disease processes involving the scrotum that have similar clinical manifestations (eg, pain, swelling, or presence of mass). The pathologic condition that may be at the origin of such symptoms can vary from testicular torsion to infection to malignancy. The ability of color and power Doppler US to demonstrate testicular perfusion aids in reaching a specific diagnosis in patients with acute scrotal pain. This review covers the anatomy of the scrotum and the scanning protocol for scrotal US, as well as detailed descriptions of disease processes and their US appearances. Newly described conditions such as intratesticular varicoceles and other benign intratesticular cystic lesions are also discussed.

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Testicular metastases from solid tumors: An autopsy study

Cited by 55 publications

References 17 publications

Diagnosis of a Contralateral Second Testicular Carcinoma by F18-FDG PET

Diagnosis of a Contralateral Second Testicular Carcinoma by F18-FDG PET

Melanoma metastases in the abdomen and pelvis: Frequency and patterns of spread

Sonography of the Scrotum

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