Testicular leiomyosarcoma with metastasis

Giridhar, Venkatesh; Kumar, Pawan; Natarajan, K; Hegde, Padmaraj

doi:10.4103/0970-1591.82854

Cited by 9 publications

(12 citation statements)

References 6 publications

(14 reference statements)

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“…Primary leiomyosarcoma of the testis is a rare entity with few cases reported in the literature [ 2 ].…”

Section: Discussionmentioning

confidence: 99%

“…Radical orchiectomy is the main treatment [ 2 ]. Chemotherapy is advised for advanced stage tumors because radiotherapy is not effective [ 19 ].…”

Section: Discussionmentioning

confidence: 99%

“…Its clinical aspects doesn't differ from other testicular malignancies, generally a painless testicular mass is the common clinical manifestation [ 3 , 2 ]. Scrotal Ultrasound usually shows a well-delineated hypoechoic mass with or without calcifications.…”

Section: Introductionmentioning

confidence: 99%

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Testicular leiomyosarcoma: A case report and literature review

Hussein¹,

Dergamoun²,

Hachem³

et al. 2021

International Journal of Surgery Case Reports

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Introduction and importance Leiomyosarcoma is a malignant mesenchymal tumor derived from the smooth muscle, it represents approximately 7% of all soft tissue sarcomas. Male genitourinary leiomyosarcomas are rare (Abdullazade et al., 2013 [ 1 ]). Primary testicular leiomyosarcoma is an exceptional entity with only 30 cases reported in the literature (Giridhar et al., 2011). Due to its rarity, additional studies are necessary to better define the optimal therapeutic management. Case presentation We report a case of a 42-years-old male diagnosed in the urology department A of the University Hospital Ibn Sina in Rabat who complains of testicular swelling. The anatomopathological examination and immunohistochemical study revealed a leiomyosarcoma therefore, a radical inguinal orchiectomy with a primary ligation of the spermatic cord was performed for diagnostic and therapeutic purposes. The assessment of extension did not reveal any lymph node location or secondary appearance thus the decision of the multidisciplinary meeting opted for regular cancer check-ups without adjuvant treatment. Discussion The actual etiology of testicular leiomyosarcoma is still unknown added to its clinical presentation and radiological results that are non-specific. Conclusion Leiomyosarcoma of the testis is a very rare tumor and its clinical and radiological presentation remains similar to other testicular malignancies.

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“…Primary leiomyosarcoma of the testis is a rare entity with few cases reported in the literature [ 2 ].…”

Section: Discussionmentioning

confidence: 99%

“…Radical orchiectomy is the main treatment [ 2 ]. Chemotherapy is advised for advanced stage tumors because radiotherapy is not effective [ 19 ].…”

Section: Discussionmentioning

confidence: 99%

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Testicular leiomyosarcoma: A case report and literature review

Hussein¹,

Dergamoun²,

Hachem³

et al. 2021

International Journal of Surgery Case Reports

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“…Its source has been recognized from smooth muscle cells from tunica propria or tunica albugínea or seminiferous tubules or blood vessel walls (4). Primary leiomyosarcoma in testis was an unusual finding with only some reported cases in published articles (5). Said that, to date, only 15 patient with primary leiomyosarcoma in testis have been reported (3).…”

Section: Discussionmentioning

confidence: 99%

Primary Testis Leiomyosarcoma: A Case Report

Nazar¹,

Shabanzadeh²,

Moghadam-Ahmadi³

et al. 2021

Iran J Pathol

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Scan to discover onlinePrimary leiomyosarcoma in testis is an uncommon tumor with few cases reported. It generally develops after radiotherapy or long-term taking anabolic steroid medication. We report a 53-year-old male patient with primary testis leiomyosarcoma who presented with painless testicular enlargement without any known predisposing factors. Ultrasound revealed a large heterogeneous left testicular solid lesion. Alpha-fetoprotein (AFP) and beta-human chorionic gonadotrophin (beta-HCG) levels in serum were normal. Left radical orchidectomy following with histology assessment established a diagnosis of primary leiomyosarcoma of testis. No data of cancer metastasis was established. The patient didn't receive any adjuvant therapy. There wasn't any evidence of recurrence after 1 year follow-up. Leiomyosarcoma must be one of the differential diagnoses of seronegative tumors in testis. The motivation for this paper is the extreme infrequency of the situation and the differential diagnosis by all expansive inguinoscrotal tumors.

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“…[1–8] This is the first case in which leiomyosarcoma metastasized to the retroperitoneal space postoperatively. Intratesticular leiomyosarcoma occurs from smooth muscle cells within the testis such as blood vessels, seminiferous tubules, and tunica.…”

Section: Discussionmentioning

confidence: 99%

Metastasis of primary testicular leiomyosarcoma to the retroperitoneal space

et al. 2012

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A 70-year-old man presented with a left scrotal swelling. A computed tomography scan showed an 8-cm left scrotal mass and no metastasis. Radical orchiectomy with high ligation of the spermatic cord was performed. The tumor was classified as a high-grade leiomyosarcoma of the left testis. An intensive follow-up including repeated computed tomography scans was performed. A computed tomography scan 34 months after the surgery showed a retroperitoneal mass in front of the left kidney. Resection of the mass was performed. Microscopically, the mass was metastatic leiomyosarcoma. Intratesticular leiomyosarcoma is rare; only 18 cases have been reported. This is the first case in which leiomyosarcoma metastasized to the retroperitoneal space postoperatively. We herein review the literature and discuss how intratesticular leiomyosarcoma metastasized to the retroperitoneal space in this patient.

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Testicular leiomyosarcoma with metastasis

Cited by 9 publications

References 6 publications

Testicular leiomyosarcoma: A case report and literature review

Testicular leiomyosarcoma: A case report and literature review

Primary Testis Leiomyosarcoma: A Case Report

Metastasis of primary testicular leiomyosarcoma to the retroperitoneal space

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