Testicular Feminization, Testes, and Testicular Tumors, Rat, Mouse

Reddy, Janardan K.; Rao, M. Sambasiva

doi:10.1007/978-3-642-72550-0_32

Cited by 3 publications

(1 citation statement)

References 20 publications

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“…Granulomatous inflammation with many macrophages may resemble vacuolated Leydig cells. Leydig cell hyperplasia has been described in Boorman et al 1987a;Boorman, Chapin, and Mitsumori 1990;Faccini, Abbott, and Paulus 1990;Frith and Ward 1988;Gordon, Majka, and Boorman 1996;Mitsumori and Elwell 1988;Prahalada et al 1994;Rao and Reddy 1987;Reddy and Rao 1987;Rehm et al 2001. Newbold, and McLachlan 1988;Newbold et al 1985).…”

Section: Non-neoplastic Proliferative Lesions: Testis Introductionmentioning

confidence: 99%

Proliferative and Nonproliferative Lesions of the Rat and Mouse Male Reproductive System

Creasy

Bube

Rijk³

et al. 2012

Toxicol Pathol

204

198

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The INHAND Project (International Harmonization of Nomenclature and Diagnostic Criteria for Lesions in Rats and Mice) is a joint initiative of the Societies of Toxicologic Pathology from Europe (ESTP), Great Britain (BSTP), Japan (JSTP), and North America (STP) to develop an internationally accepted nomenclature for proliferative and nonproliferative lesions in laboratory animals. The purpose of this publication is to provide a standardized nomenclature and differential diagnosis for classifying microscopic lesions observed in the male reproductive system of laboratory rats and mice, with color microphotographs illustrating examples of some lesions. The standardized nomenclature presented in this document is also available for society members electronically on the Internet (http://goreni.org). Sources of material included histopathology databases from government, academia, and industrial laboratories throughout the world. Content includes spontaneous and aging lesions as well as lesions induced by exposure to test materials. A widely accepted and utilized international harmonization of nomenclature for lesions of the male reproductive system in laboratory animals will decrease confusion among regulatory and scientific research organizations in different countries and provide a common language to increase and enrich international exchanges of information among toxicologists and pathologists.

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