Testicular descent, cryptorchidism and inguinal hernia: the Melbourne perspective

Tomiyama, Hideki; Sasaki, Yoshitaka; Huynh, Jenny; Yong, Eric; Ting, Alvin; Hutson, John M.

doi:10.1016/j.jpurol.2004.11.001

Cited by 36 publications

(29 citation statements)

References 140 publications

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“…It is widely accepted that androgens are required for normal abdominal translocation of the testes (Boisen et al, 2004;Swan et al, 2005;Tomiyama et al, 2005;Scott et al, 2009). Therefore, a particular strength of this study is the use of two complementary rat models to support the contention that the association between analgesic use and cryptorchidism seen in our cohort study may result from a reduction in androgen production.…”

Section: Discussionmentioning

confidence: 61%

Intrauterine exposure to mild analgesics is a risk factor for development of male reproductive disorders in human and rat

et al. 2010

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Section: Discussionmentioning

confidence: 61%

Intrauterine exposure to mild analgesics is a risk factor for development of male reproductive disorders in human and rat

et al. 2010

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“…The first (transabdominal) phase is proposed to occur when the testis descends from its initial position in the abdomen into the inguinal region. The second (inguinoscrotal) phase is when the testis migrates from the inguinal region across the pubis and into the scrotum [1,2]. There is considerable evidence that the inguinoscrotal phase is controlled by androgen acting mostly indirectly on the gubernaculum via the genitofemoral nerve and by the release of calcitonin gene-related peptide (CGRP) [1,2].…”

mentioning

confidence: 99%

Calcitonin gene-related peptide is a survival factor, inhibiting apoptosis in neonatal rat gubernaculum in vitro

Chan

Farmer

Southwell

et al. 2009

Journal of Pediatric Surgery

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“…The term cryptorchidism is derived from the Greek words 'Kryptos 'meaning 'hidden' and 'orchis' meaning testes (Tomiyama et al, 2005).…”

Section: Discussionmentioning

confidence: 99%

Study of Undescended Testes by High Frequency Ultrasound

Onkar

Mitra

2012

Int. J. Morphol.

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SUMMARY:Undescended testes or cryptorchidism in the most common congenital anomaly of male reproductive system. The descent is multifactorial with gubernaculums playing major role. The failure of descent can be at trans-abdominal or inguino-scrotal phase. Locating undescended testes is important in view of low fertility and high rate of occurrence of neoplasm in them. Ultrasound is the standard imaging technique of choice in children with a non-palpable testis as it is non-invasive and does not use ionizing radiation. Position of testis is also important in deciding whether patient will need abdominal or inguinal exploration. The aim was to study the position of undescended testes by high frequency ultrasound and its embryonic explanation. Total 41 boys with undescended testes underwent high frequency ultrasound. The location of testis was noted followed by its size and echotexture. Thirty patients had unilateral and 11 had bilateral undescended testes. The prevalence was more on right side (16 out of 30). Out of total 52, 46 (88%) testis were located by ultrasound. Six (12%) testes could not be located. Five (10%) were retractile testes. Out of remaining 41, 26 (63%) were located in inguinal canal and 15 (37%) were located in abdomen. Out of 15 abdominal testes 9 were located just proximal to inguinal canal and 6 were located in deep pelvis. High frequency ultrasound was able to locate the position of undescended testes in majority (88%) of the cases.

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Testicular descent, cryptorchidism and inguinal hernia: the Melbourne perspective

Cited by 36 publications

References 140 publications

Intrauterine exposure to mild analgesics is a risk factor for development of male reproductive disorders in human and rat

Intrauterine exposure to mild analgesics is a risk factor for development of male reproductive disorders in human and rat

Calcitonin gene-related peptide is a survival factor, inhibiting apoptosis in neonatal rat gubernaculum in vitro

Study of Undescended Testes by High Frequency Ultrasound

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