Testicular damage without clinical manifestations in BALB/c mice experimentally infected with Zika virus
Derick Mendes Bandeira,
Arthur da Costa Rasinhas,
Raphael Leonardo
et al.
Abstract:In 2015-2016, the Zika virus (ZIKV) caused a major epidemic in the Americas, increasing cases of microcephaly and Guillain-Barré syndrome. During this period, the discovery of ZIKV sexual transmission intensified studies on the impact of this virus on the reproductive organs. For this study, 2-month-old male BALB/c mice were infected with 1.26 x 10
6
PFU/mL of ZIKV in solution via the intravenous route. After three, seven, and fourteen days post-infection (DPI), blood and testicle sample… Show more
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