Testagem inicial e capacidade discriminatória da escala "UFMG Syedenha's Chorea Rating Scale (USCRS)"

Abstract

Recentemente desenvolvemos e validamos a escala "Universidade Federal de Minas Gerais (UFMG) Sydenham’s Chorea Rating Scale" (USCRS) para avaliar sistematicamente os pacientes com coréia de Sydenham (CS). Neste estudo, examinamos 97 crianças e adultos com CS (média de idade ± desvio padrão, 15,5 ± 5,9; masculino/feminino, 31/66) acompanhados na Clínica de Distúrbios do Movimento da UFMG, empregando a escala USCRS. Os pacientes foram divididos em 4 grupos conforme a forma clínica apresentada: aguda (n=19), recorrente (n=17), persistente (n=19) e remissão (n=42). O escore médio ± erro padrão na escala USCRS para cada um dos grupos foi, respectivamente, 47,7 ± 4,7 para aguda, 29,5 ± 2,6 para recorrente, 17,6 ± 3,1 para persistente e 1,1 ± 0,2 para remissão. Todas as comparações entre cada um dos grupos foram estatisticamente significativas (p<0,05). Nossos resultados sugerem que a escala USCRS pode discriminar razoavelmente os grupos de pacientes com em diferentes formas clínicas de CS.

Treatment of Sydenham Chorea With Intravenous Immunoglobulin

“…It uses a score ranging from 0 to 16 that rates the severity from mild chorea to the most severe form known as chorea mollis (Table 2). 5,15,31,32 The scale by Teixeira et al-the Universidade Federal de Minas Gerais Sydenham's Chorea Rating Scale assesses behavior, functionality as reflected by ability to perform activities of daily living, and motor function. 31 There are 27 items with each one scored from 0 (no symptom or sign) to 4 (severe disability or finding).…”

Intravenous immunoglobulin in acute Sydenham's chorea: A systematic review

“…A diagnosis of acute rheumatic fever (ARF) with Sydenham's chorea (SC) as a major feature was made, as per the revised Jones criteria . She was given 2 g/kg of intravenous immunoglobulin (IVIg) in the acute phase and monitored with serial Unified SC Rating Scale (USCRS) scores, which normalised over a 3‐month period (45/108 at onset, 18/108 at 3‐week follow‐up and 2/108 at 3‐month follow‐up). The USCRS contains six behaviour items, seven activities of daily living (ADL) items and 14 motor items; the total score ranges from 0 to 108, with 108 indicating maximum severity.…”

Monocyte dysfunction in Sydenham's chorea patients

“…SC was diagnosed if the patient met the modified Jones Criteria for acute rheumatic fever [16] and if other causes of chorea were carefully excluded [17]. At diagnosis, all SC patients had echocardiographic signs of carditis represented by mild mitral insufficiency [18]. SC patients were in remission and were using only penicillin-G benzathine for RF prophylaxis.…”