Test performance and clinical utility of expanded non‐invasive prenatal test: Experience on 71,883 unselected routine cases from one single center
Monica Faieta,
Rossella Falcone,
Sara Duca
et al.
Abstract:ObjectiveThe balance between benefits and risks of discordant outcomes makes the Genome‐Wide Non‐Invasive Prenatal Test (GW‐NIPT) controversial. This study aims to evaluate performance and clinical utility in a wide cohort of unselected clinical cases from a single center when a standardized protocol is applied and integrated with a secondary algorithm for data interpretation.MethodIn 2 years, over 70,000 pregnant patients underwent GW‐NIPT for fetal common trisomies, sex chromosome aneuploidies, rare autosoma… Show more
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