Test mass alignment using overlapped-flexure hinge in NIM-2 joule balance

Wang, Dawei; Bai, Yang; Liu, Yongmeng; Li, Zhengkun; Tan, Jiubin

doi:10.1016/j.measurement.2020.107685

Cited by 2 publications

(2 citation statements)

References 14 publications

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“…Compared with the traditional rigid mechanism, it has many advantages, including no gap, no friction, small size, lightweight, integrated design and processing, no assembly, and high precision. It is widely applied in precision positioning and other fields [ 21 , 22 ].…”

Section: Structural Designmentioning

confidence: 99%

Piezoelectric Ultrasonic Biological Microdissection Device Based on a Novel Flexure Mechanism for Suppressing Vibration

et al. 2021

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Biological microdissection has a wide range of applications in the field of molecular pathology. The current laser-assisted dissection technology is expensive. As an economical microdissection method, piezoelectric ultrasonic microdissection has broad application prospects. However, the performance of the current piezoelectric ultrasonic microdissection technology is unsatisfactory. This paper aims to solve the problems of the low dissecting precision and excessive wear of the dissecting needle caused by the harmful lateral vibration of the present piezoelectric ultrasonic microdissection device. A piezoelectric ultrasonic microdissection device based on a novel flexure mechanism is proposed. By analyzing the flexure hinge flexibility, the type of flexure beam and the optimal design parameters are determined. Through harmonic response simulation analysis, the newly designed microdissection device with a vibration-suppressing mechanism achieves the best vibration effect when the driving frequency is 28 kHz. Under this driving frequency, the lateral vibration suppression effect is improved by 68% compared to the traditional effect without vibration suppression. Then, based on 3D printing technology, a prototype of a novel microdissection device is produced, and its performance is tested. Experiments on dissecting needle vibration tests show that the flexure mechanism does indeed suppress the lateral vibration of the needle tip. We conducted various tissue dissection experiments on paraffin tissue sections. First, we determine the optimal dissecting parameters (driving voltage, frequency, feed speed, cutting angle) of the new equipment through various parameter dissecting experiments. Then, we adopt these optimal dissecting parameters to perform three kinds of dissecting experiments on mouse tissue paraffin section (liver, lung, bone), dissecting experiments on tissue sections of different thicknesses (3 μm, 4 μm, 5 μm), sampling and extraction experiments on complete tissue. The new device has a better dissecting performance for paraffin tissue sections below a 5 μm thickness and can complete various dissecting tasks. Finally, we compare the wear of the dissecting needles of the new and old devices after the same dissecting tasks. The results prove that the suppression of harmful lateral vibration not only significantly improves the dissecting effect but also increases the service life and durability of the dissecting needle, which is beneficial for reducing the equipment costs.

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Section: Structural Designmentioning

confidence: 99%

Piezoelectric Ultrasonic Biological Microdissection Device Based on a Novel Flexure Mechanism for Suppressing Vibration

et al. 2021

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“…Therefore, the mass exchanging procedure has a very small effect on the postures of the coil, and its effect on the coil position is also very limited. The violent oscillation of the coil is caused by the mass touching of the pan during the loading process, and it decays rapidly because of the magnetic damping [14].…”

Section: The Alignmentsmentioning

confidence: 99%

The upgrade of NIM-2 joule balance since 2017

Bai

et al. 2020

Metrologia

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In 2017, we published the first measurement result with the NIM-2 joule balance and the relative standard uncertainty was 2.4 × 10 −7 . Since then, a series of improvements have been carried out to upgrade the NIM-2 joule balance towards the 10 -8 level relative uncertainty. The main improvements include a permanent magnet, as well as a two-layer magnetic shield to decrease the main uncertainty contribution from the external magnetic field, a parasitic displacement measurement system and a new suspension for improving alignments, and a new mass translation stage constructed with all non-magnetic materials. In September 2019, when the NIM-2 joule balance was used to calibrate a 1 kg mass, the type A relative standard uncertainty had been reduced to 3 × 10 −8 (k = 1) and the combined relative standard uncertainty was less than 1 × 10 −7 (k = 1). In October and November 2019, a 1 kg Pt/Ir mass and a 1 kg stainless steel mass were measured with the NIM-2 joule balance, and the relative standard uncertainties were 5.2 × 10 −8 and 6.5 × 10 −8 , respectively. The relative difference between the measured values and the calibration values obtained from the mass group were 4 × 10 −9 and 3 × 10 −8 , respectively.

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Test mass alignment using overlapped-flexure hinge in NIM-2 joule balance

Cited by 2 publications

References 14 publications

Piezoelectric Ultrasonic Biological Microdissection Device Based on a Novel Flexure Mechanism for Suppressing Vibration

Piezoelectric Ultrasonic Biological Microdissection Device Based on a Novel Flexure Mechanism for Suppressing Vibration

The upgrade of NIM-2 joule balance since 2017

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