Terrestrial health applications of visual assessment technology and machine learning in spaceflight associated neuro-ocular syndrome

Ong, Joshua; Tavakkoli, Alireza; Zaman, Nasif; Kamran, Sharif Amit; Waisberg, Ethan; Gautam, Nikhil; Lee, Andrew G.

doi:10.1038/s41526-022-00222-7

Cited by 49 publications

(25 citation statements)

References 77 publications

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“…To address this issue, a headmounted, multi-modal visual assessment system is currently being built to help detect the subtle visual impacts of SANS. 17,18 This project is supported by NASA with the goal of developing a noninvasive framework for astronaut vision. 19 Head-mounted technology has many benefits over traditional forms of visual assessment, as it can use eye-tracking technology, with consistent illumination, be performed rapidly, and with minimal set-up required.…”

Section: Challenges and Future Directionsmentioning

confidence: 99%

The Case for Expanding Visual Assessments During Spaceflight

Waisberg

Ong

Masalkhi

et al. 2023

Prehosp. Disaster med.

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Spaceflight associated neuro-ocular syndrome (SANS) is one of the potential barriers to human long-duration spaceflight (LDSF), including a manned mission to Mars. While a large barrier, the pathophysiology of SANS is not well understood, and functional and structural findings from SANS continue to be further characterized. Currently on the International Space Station (ISS), scheduled visual assessments are static visual acuity, Amsler grid, and a self-reported survey. Additional visual assessments may help the understanding of this neuro-ophthalmic phenomenon, as well as the effects of spaceflight of overall ocular health. In this paper, a case is made for expanding scheduled visual assessments to include dynamic visual, contrast sensitivity (CS), visual field testing, and virtual reality-based metamorphopsia assessment during spaceflight. These further assessments may play a key role in helping to determine the structural and functional changes associated with SANS, which are crucial to maintain astronaut vision during LDSF, as well as for developing countermeasures. Finally, a brief discussion is provided about current challenges to expanding visual testing during spaceflight and potential solutions to these barriers, specifically head-mounted visual assessment technology.

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Section: Challenges and Future Directionsmentioning

confidence: 99%

The Case for Expanding Visual Assessments During Spaceflight

Waisberg

Ong

Masalkhi

et al. 2023

Prehosp. Disaster med.

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“…Specifically, more methods of noninvasive data collection are needed in space, such as biosensors. Our group has been developing a multi-modal headmounted headset with the goal of helping collect more vision data during spaceflight to further understand the impacts of microgravity on the visual system [20,21]. Astronaut data represents data from a special cohort and has several unique limitations: this data belongs to an extremely small population, that is, majority middle-aged, male, and white Americans.…”

Section: Limited Astronaut Data For Training and Validationmentioning

confidence: 99%

Challenges of Artificial Intelligence in Space Medicine

et al. 2022

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The human body undergoes many changes during long-duration spaceflight including musculoskeletal, visual, and behavioral changes. Several of these microgravity-induced effects serve as potential barriers to future exploration missions. The advent of artificial intelligence (AI) in medicine has progressed rapidly and has many promising applications for maintaining and monitoring astronaut health during spaceflight. However, the austere environment and unique nature of spaceflight present with challenges in successfully training and deploying successful systems for upholding astronaut health and mission performance. In this article, the dynamic barriers facing AI development in space medicine are explored. These diverse challenges range from limited astronaut data for algorithm training to ethical/legal considerations in deploying automated diagnostic systems in the setting of the medically limited space environment. How to address these challenges is then discussed and future directions for this emerging field of research.

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“…1 The large increase of individuals travelling to space will create a population that is more diverse, both in terms of age and in medical comorbidities (such as vasculopathic risk factors). 2 The understanding of space medicine and potential physiological risks of spaceflight will only become more important for doctors to understand in the future.…”

Section: Introductionmentioning

confidence: 99%

Space Medicine: The Next Frontier of Medical Education

Waisberg

Ong

Masalkhi

et al. 2023

Prehosp. Disaster med.

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Spaceflight has always been met with awe by the general public and may also have strong implications for medical training for future physicians, regardless of specialty or practice. Within the near future, the commercialization of spaceflight will lead to an unprecedented surge in travelers to space. With this increase, the understanding of space medicine and potential physiological risks of microgravity will only become more important for doctors to understand. Historically, teaching education on how the body responds to various different environments and environmental changes has been a longstanding core to medical education. Thus, education about the physiological, pathologic, and histologic changes to weightlessness over prolonged periods of time will likely provide additional insights to space medicine, as well as how medicine can be practiced here on Earth. The addition of space medicine to the medical curriculum will likely not only benefit future space medicine physicians, but also likely benefit all physicians and human health on Earth. In this manuscript, we discuss the various risks that astronauts undergo, as well as current space medicine education initiatives on Earth.

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Terrestrial health applications of visual assessment technology and machine learning in spaceflight associated neuro-ocular syndrome

Cited by 49 publications

References 77 publications

The Case for Expanding Visual Assessments During Spaceflight

The Case for Expanding Visual Assessments During Spaceflight

Challenges of Artificial Intelligence in Space Medicine

Space Medicine: The Next Frontier of Medical Education

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