Terpenoids

Hill, Robert A.

doi:10.1007/978-94-011-2144-6_3

Cited by 10 publications

(3 citation statements)

References 180 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Terpenoids are one of the largest classes of chiral natural compounds, which includes more than 23,000 compounds. Many terpene derivatives are widely used in perfumes, playing the role of cosmetic products and food additives [ 3 ]. However, medicine is not less important area of application of terpenes, since the majority of compounds of this class exhibits pronounced biological activity.…”

Section: Introductionmentioning

confidence: 99%

Synthesis of Carvone-Derived 1,2,3-Triazoles Study of Their Antioxidant Properties and Interaction with Bovine Serum Albumin

et al. 2018

View full text Add to dashboard Cite

Natural L-carvone was utilized as a starting material for an efficient synthesis of some terpenyl-derived 1,2,3-triazoles. Chlorination of carvone, followed by nucleophilic substitution with sodium azide resulted in the preparation of 10-azidocarvone. Subsequent CuAAC click reaction with propargylated derivatives provided an efficient synthetic route to a set of terpenyl-derived conjugates with increased solubility in water. All investigated compounds exhibit high antioxidant activity, which is comparable with that of vitamin C. It was also found that serum albumin and the terpenyl-1,2,3-triazoles hybrids spontaneously undergo reversible binding driven by hydrophobic interactions, suggesting that serum albumin can transport the target triazoles.

show abstract

Section: Introductionmentioning

confidence: 99%

Synthesis of Carvone-Derived 1,2,3-Triazoles Study of Their Antioxidant Properties and Interaction with Bovine Serum Albumin

et al. 2018

View full text Add to dashboard Cite

show abstract

“…Esters of ingol, lathyrane and phorbol, which is a tigliane, are clearly derived from the ingenane skeleton. 8 These esters possess potent biological activities. Phorbol, in particular, interacts with the C1 domain 9 of the protein kinase C super-family, 10 which is conserved among a large number of species.…”

Section: Introductionmentioning

confidence: 99%

ESTs from Seeds to Assist the Selective Breeding of Jatropha curcas L. for Oil and Active Compounds

et al. 2010

View full text Add to dashboard Cite

We report here on the characterization of a cDNA library from seeds of Jatropha curcas L. at three stages of fruit maturation before yellowing. We sequenced a total of 2200 clones and obtained a set of 931 non-redundant sequences (unigenes) after trimming and quality control, ie, 140 contigs and 791 singlets with PHRED quality ≥10. We found low levels of sequence redundancy and extensive metabolic coverage by homology comparison to GO. After comparison of 5841 non-redundant ESTs from a total of 13193 reads from GenBank with KEGG, we identified tags with nucleotide variations among J. curcas accessions for genes of fatty acid, terpene, alkaloid, quinone and hormone pathways of biosynthesis. More specifically, the expression level of four genes (palmitoyl-acyl carrier protein thioesterase, 3-ketoacyl-CoA thiolase B, lysophosphatidic acid acyltransferase and geranyl pyrophosphate synthase) measured by real-time PCR proved to be significantly different between leaves and fruits. Since the nucleotide polymorphism of these tags is associated to higher level of gene expression in fruits compared to leaves, we propose this approach to speed up the search for quantitative traits in selective breeding of J. curcas. We also discuss its potential utility for the selective breeding of economically important traits in J. curcas.

show abstract

“…Hidrocarbonetos terpênicos e seus derivados oxifuncionalizados (terpenóides) constituem a classe de substâncias mais diversa na natureza (Hill 1993). Os terpenos são os responsáveis pelo aroma dos óleos essenciais, além de serem ótimos substratos para conversões estereoespecíficas.…”

Section: Introdução Geralunclassified

Biotransformação de terpenos para a produção de compostos de aroma e funcionais

Maróstica¹,

Pastore²

View full text Add to dashboard Cite

A meus pais, Mário e Beth, que me fazem sentir o gosto pela vida a cada instante vivido, a cada palavra proferida. Dedico-lhes com o mesmo infinito amor que eles incessantemente me dedicam a cada passo de nossa convivência.v AgradecimentosA meus pais, Mário e Beth, pelo apoio incondicional, irrestrito e constante, pelos imensuráveis esforços à minha formação. Vocês foram a sustentação para que esse trabalho fosse possível.À Carol, minha querida, pelos abraços ternos, pelo sorriso meigo e pelo amor incessante.À Thaís, minha irmã, pelo apoio e amizade.A meus avós Arlindo (in memorian), Nancy, Olívio e Lúcia por todo o apoio.À tia Odila pelos sábios conselhos e todo o carinho. À profa. Gláucia, por toda a orientação, amizade, por toda a confiança em mim depositada, pela oportunidade, por despertar em mim a crescente vontade de saber, de aprender, de conhecer, de me dedicar mais e mais e por me ajudar a desenvolver o senso crítico e a vontade de vencer os desafios.

show abstract

Terpenoids

Cited by 10 publications

References 180 publications

Synthesis of Carvone-Derived 1,2,3-Triazoles Study of Their Antioxidant Properties and Interaction with Bovine Serum Albumin

Synthesis of Carvone-Derived 1,2,3-Triazoles Study of Their Antioxidant Properties and Interaction with Bovine Serum Albumin

ESTs from Seeds to Assist the Selective Breeding of Jatropha curcas L. for Oil and Active Compounds

Biotransformação de terpenos para a produção de compostos de aroma e funcionais

Contact Info

Product

Resources

About