Terpenoid from Indonesian temu mangga (Curcuma mangga, Val) rhizomes and review of its anticancer towards MCF-7 breast cells

Ganur, Alicia N. A.; Rahayu, D. U. C.; Dianhar, Hanhan; Irwanto, Ichsan; Sugita, Purwantiningsih

doi:10.1063/5.0051538

4th International Seminar on Chemistry 2021

DOI: 10.1063/5.0051538

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Terpenoid from Indonesian temu mangga (Curcuma mangga, Val) rhizomes and review of its anticancer towards MCF-7 breast cells

Alicia N. A. Ganur

D. U. C. Rahayu

Hanhan Dianhar

et al.

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Cited by 2 publications

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“…15 Since then, many naturally occurring anticancer drugs have been identified. 16,17 Despite the recent dominance of synthetic chemistry as a method to discover and produce drugs, there is still enormous potential for bioactive plants or their extracts to provide new and novel products for disease treatment and prevention. 18,19 Plants have an almost unlimited capacity to produce substances that attract researchers in the quest for novel chemotherapeutics.…”

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In Vitro Anticancer Activity of Hexane and Ethyl acetate Extracts of Leaf, Petiole and Rhizome of Petasites japonicus

2023

TJNPR

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Cancer is one of the most dangerous diseases in humans; accordingly, there is considerable demand for discovery of new anticancer agents from natural products. [12][13][14] The potential for using natural products as anticancer drugs was recognized in 1950 by the United States Natural Cancer Institute (NCI). 15 Since then, many naturally occurring anticancer drugs have been identified. 16,17 Despite the recent dominance of synthetic chemistry as a method to discover and produce drugs, there is still enormous potential for bioactive plants or their extracts to provide new and novel products for disease treatment and prevention. 18,19 Plants have an almost unlimited capacity to produce substances that attract researchers in the quest for novel chemotherapeutics. 18 The continuing search for new anticancer compounds in plants and traditional foods is a realistic and promising strategy for its prevention. 20 The objective of this study was to investigate the anticancer activity of the hexane, ethyl acetate, butanol and aqueous fractions of extract of Petasites japonicus Max plant parts against four human cancer cell lines. Materials and Methods Plant materialsWild Petasites japonicus Max was collected in September 2019 from Chungdogun, Gyungbuk Province, Korea, and processed and divided into leaves, petioles, and rhizomes. The plant species was verified by Dr. Young Whan Choi, and a voucher specimen (No.

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In Vitro Anticancer Activity of Hexane and Ethyl acetate Extracts of Leaf, Petiole and Rhizome of Petasites japonicus

2023

TJNPR

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Genus Curcuma: chemical and ethnopharmacological role in aging process

Elhawary,

Moussa,

Singab

2024

BMC Complement Med Ther

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Aging or senescence is part of human life development with many effects on the physical, mental, and physiological aspects which may lead to age-related deterioration in many organs. Genus Curcuma family Zingieraceae represents one of the well-studied and medically important genera with more than eighty species. The genus is reported to contain different classes of biologically active compounds that are mainly presented in diphenylheptanoids, diphenylpentanoids, diphenylalkanoids, phenylpropene derivatives, alkaloids, flavonoids, chromones, terpenoids, phenolic acids and volatile constituents. Rhizomes and roots of such species are rich with main phytoconstituents viz. curcumin, demethoxycurcumin and bis-demethoxycurcumin. A wide variety of biological activities were demonstrated for different extracts and essential oils of genus Curcuma members including antioxidant, anti-inflammatory, cytotoxic and neuroprotective. Thus, making them as an excellent safe source for nutraceutical products and as a continuous promising area of research on lead compounds that may help in the slowing down of the aging process especially the neurologic and mental deterioration that are usually experienced upon aging. In this review different species of the genus Curcuma were summarized with their phytochemical and biological activities highlighting their role as antiaging agents. The data were collected from different search engines viz. Pubmed®, Google Scholar®, Scopus® and Web of Science® limiting the search to the period between 2003 up till now.

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Terpenoid from Indonesian temu mangga (Curcuma mangga, Val) rhizomes and review of its anticancer towards MCF-7 breast cells

Cited by 2 publications

References 32 publications

In Vitro Anticancer Activity of Hexane and Ethyl acetate Extracts of Leaf, Petiole and Rhizome of Petasites japonicus

In Vitro Anticancer Activity of Hexane and Ethyl acetate Extracts of Leaf, Petiole and Rhizome of Petasites japonicus

Genus Curcuma: chemical and ethnopharmacological role in aging process

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