Terpenes with antimicrobial and antioxidant activities from Lannea humilis (Oliv.)

Achika, J.I.; Ayo, Rachael Gbekele-Oluwa; Habila, James D.; Oyewale, A. O.

doi:10.1016/j.sciaf.2020.e00552

Cited by 10 publications

(8 citation statements)

References 13 publications

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“…The crude pigment extracts used in this study contains phenols and terpenes. In accordance to Zeb [21], Achika et al [27], and Wang et al [28] which stated that phenols and terpenes contributed in antioxidant activity. Therefore, the antioxidant activity (radical scavenging activity) may result from the coexistence of phenolic and terpenoid-type compounds [16,20,21].…”

Section: Resultssupporting

confidence: 70%

Antioxidant and antimicrobial screening of an unidentified yellow pigmented marine-derived fungus

Octaverina,

Sibero,

Subagiyo

et al. 2023

IOP Conf. Ser.: Earth Environ. Sci.

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The exploration of fungal secondary metabolites has increased significantly since the first discovery of penicillin. In addition, pigment derived from marine fungi attracts plenty of attention due to its complex and unusual chemical structures, which have tremendous antioxidants and antimicrobial activities. Hence, our current work aimed to characterize the crude pigment extract of an unidentified fungus SUCCF0001 and its potential as an antioxidant and antimicrobial agent. The fungus was cultivated on two semi-solid media namely MEA and PDA for 14 days at 25 °C, and two different liquids media namely MEB and PDB for 14 days at 25 °C with agitation at 150 r.p.m. The semi-solid medium and the fungal mycelium from the broth culture were extracted with methanol, while the liquid medium using ethyl acetate. The crude extracts were characterized using TLC plates and then visualized using DPPH, vanillin-H2SO4, and FeCL3. The presence of carotenoid pigment was detected using TLC with β-carotene as a marker. Antioxidant bioassay was screened using the DPPH method; while antimicrobial activity bioassay was conducted using the paper disc method against Bacillus subtilis, Escherichia coli, Micrococcus luteus, Pseudomonas aeruginosa and Candida tropicalis. The results showed that only the PDB extract had radical scavenging activity (RSA) > 50% for antioxidant activity. On the other hand, antimicrobial bioassay showed that only MEB extract had antimicrobial activity against B. subtilis. TLC analysis indicated the presence of antioxidants, terpenoids and phenols in both PDB and MEB extract. However, the result of fungal pigment characterization using TLC concluded that the pigment was not a β-carotene.

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Section: Resultssupporting

confidence: 70%

Antioxidant and antimicrobial screening of an unidentified yellow pigmented marine-derived fungus

Octaverina,

Sibero,

Subagiyo

et al. 2023

IOP Conf. Ser.: Earth Environ. Sci.

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“…In addition to lignans, terpenes can also play an important role in antibacterial activity and insect resistance. [57][58][59] A variety of alkaloid metabolites synthesized by plants were found to be significantly toxic to insect growth and development. 19 For example, tannin is a kind of polyphenol that inhibits the digestive enzymes of herbivorous insects 18 and thus affects insect growth and development.…”

Section: Discussionmentioning

confidence: 99%

“…3(e)). In addition to lignans, terpenes can also play an important role in antibacterial activity and insect resistance 57–59 . A variety of alkaloid metabolites synthesized by plants were found to be significantly toxic to insect growth and development 19 .…”

Section: Discussionmentioning

confidence: 99%

Helicoverpa armigera herbivory negatively impacts Aphis gossypii populations via inducible metabolic changes

Zheng

Liu

Luo

et al. 2022

Pest Management Science

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BACKGROUND: Helicoverpa armigera and Aphis gossypii are two important insect species that feed on cotton plants. These insects have distinct abilities to induce plant resistance and tolerate plant toxins, which results in interspecific competition imbalance that may be fatal to the low-tolerance A. gossypii and force these insects to develop avoidance behaviors and subsequently separate from their niche. We implemented ecological experiments to test the effects of H. armigera-induced plant resistance and behavioral avoidance in A. gossypii, and employed transcriptomics and metabolomics analyses to reveal changes in resistance genes and metabolites in plants.RESULTS: Our results demonstrate that cotton plants induced by H. armigera cause significant inhibitory and avoidance effects on A. gossypii insect populations. Electrical penetration graph (EPG) analysis showed changes in plant resistance induced by H. armigera leading to a decreased feeding efficiency of A. gossypii. In addition, genes associated with jasmonic acid and ethylene signaling pathways were significantly up-regulated in cotton plants after H. armigera induction, which led to a significant up-regulation of metabolites inducing plant resistance. These observations were corroborated by bioactivity analysis on metabolites, which showed that jasmonic acid, gossypol and tannins have significant inhibitory effects on A. gossypii populations. In contrast, methylparaben is associated with avoidance behaviors on A. gossypii populations.CONCLUSION: Our study suggests that the differences in the ability to induce plant resistance and tolerance between two non-predatory insects were lethal to low-tolerance A. gossypii insects, which might be a major factor determining their niche differentiation. This was further demonstrated by screening anti-insect and bio-hormonal metabolites. Our study provides a reference for investigating the evolutionary relationship between non-predatory insects and insights to implement effective insect biocontrol.

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“…Plant natural products have an important biomedical source playing a major role in drug discovery. The Anacardiaceae family, especially Lannea species are the site of multiple sources of secondary metabolites such as terpenes, polyphenol [1] [2] [3] [4] alkenyl phenols and alkenyl cyclohexenones [5], steroid [6] [4] and ceramide [7]. Lannea species have numerous pharmacological properties such as antibacterial [4] [5] [8], antoxidant [7] [8] [9], anticancer [10] [11] [12], antihypertensive [13].…”

Section: Introductionmentioning

confidence: 99%

“…Nine (1)(2)(3)(4)(5)(6)(7)(8)(9) naturally-occurring compounds including three undescribed (1)(2)(3) were characterized from n-butanol fraction of L. kerstingii leaves.…”

Section: Introductionmentioning

confidence: 99%

New C-13 Norisoprenoids and Flavonoids from <i>Lannea kerstingii</i>

Koffi¹,

Yao-Kouassi²,

Seri³

et al. 2022

MSCE

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Lannea kerstingii is known for its multiple therapeutic and biological activities. Despite of many traditional uses of this plant, scientific research on the content of its chemical compounds is still limited. This study aims to isolate the chemical compounds contained in the n-butanol fraction of Lannea kerstingii leaves. The chemical investigation of the leaves of Lannea kerstingii led to isolation of three undescribed C-13 norisoprenoids, lankerstinol A-C (1-3), together with six (4-9) known flavonoid glycosides. The structures of these compounds were established by spectroscopic analyses.

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Terpenes with antimicrobial and antioxidant activities from Lannea humilis (Oliv.)

Cited by 10 publications

References 13 publications

Antioxidant and antimicrobial screening of an unidentified yellow pigmented marine-derived fungus

Antioxidant and antimicrobial screening of an unidentified yellow pigmented marine-derived fungus

Helicoverpa armigera herbivory negatively impacts Aphis gossypii populations via inducible metabolic changes

New C-13 Norisoprenoids and Flavonoids from <i>Lannea kerstingii</i>

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Terpenes with antimicrobial and antioxidant activities from Lannea humilis (Oliv.)

Cited by 10 publications

References 13 publications

Antioxidant and antimicrobial screening of an unidentified yellow pigmented marine-derived fungus

Antioxidant and antimicrobial screening of an unidentified yellow pigmented marine-derived fungus

Helicoverpa armigera herbivory negatively impacts Aphis gossypii populations via inducible metabolic changes

New C-13 Norisoprenoids and Flavonoids from &lt;i&gt;Lannea kerstingii&lt;/i&gt;

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New C-13 Norisoprenoids and Flavonoids from <i>Lannea kerstingii</i>