Terpenes from Mikania aff. jeffreyi (Asteraceae)

Mendes, Carla C.; Cruz, Frederico G.; Guédès, Michel; Roque, Nı́dia Franca

doi:10.1515/znb-2005-0810

Cited by 8 publications

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“…pyramidalis [39], Chromolaena collina [40], Cupressus sempervirens [41,42], J. communis [43], Chloranthus spicatus [44], Sabina vulgaris Antoine [45], Torreya jackii [46], Dacrydium pierrei [47], J. phoenicea [48], Calocedrus formosana [49], Fleischmannia multinervis [50], Cretan propolis [51], Libocedrus chevalieri [52], Pinus densiflora [53], and Mikania aff. jeffreyi [54], Chamaecyparis lawsoniana [55]. Cis -communic acid ( 2 ) was detected in Larix dahurica [56], Pseudotsuga wilsoniana [57], and Cladonia rangiferina L. Web.…”

Section: Sourcesmentioning

confidence: 99%

Communic Acids: Occurrence, Properties and Use as Chirons for the Synthesis of Bioactive Compounds

et al. 2012

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Communic acids are diterpenes with labdane skeletons found in many plant species, mainly conifers, predominating in the genus Juniperus (fam. Cupresaceae). In this review we briefly describe their distribution and different biological activities (anti- bacterial, antitumoral, hypolipidemic, relaxing smooth muscle, etc.). This paper also includes a detailed explanation of their use as chiral building blocks for the synthesis of bioactive natural products. Among other uses, communic acids have proven useful as chirons for the synthesis of quassinoids (formal), abietane antioxidants, ambrox and other perfume fixatives, podolactone herbicides, etc., featuring shorter and more efficient processes.

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Section: Sourcesmentioning

confidence: 99%

Communic Acids: Occurrence, Properties and Use as Chirons for the Synthesis of Bioactive Compounds

et al. 2012

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Structural Characterization and Biological Evaluation of 18‐Nor‐ent‐labdane Diterpenoids from Grazielia gaudichaudeana

Balbinot

Oliveira

Bernardi

et al. 2019

Chemistry & Biodiversity

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The phytochemical investigation of Grazielia gaudichaudeana aerial parts yielded 15 compounds, including diterpenes, triterpenes, sterols and flavonoids. With exception to ent‐kaurenoic acid diterpenes, the compounds isolated are being described for the first time in this species. Some unusual 1H‐NMR chemical shifts of 18‐nor‐ent‐labdane (7–9) led us carry out a conformational analysis by theoretical calculations in order to support the experimental data. Moreover, due to the limitation of studies focused on pharmacological potential of Grazielia gaudichaudeana, the present study was carried out to investigate the antioxidant, antiproliferative, antiviral, antileishmanial and antimicrobial activities from the extract, fractions and isolated compounds obtained from this species. Ethyl acetate fraction showed significant activity in the antiproliferative assay, with GI50 range of 3.9 to 27.2 μg mL−1. Dichloromethane fraction, rich in diterpenoids, inhibited all human tumor cell lines tested, and the nor‐labdane 7 showed potent cytotoxic activity against glioma and ovary cancer cell lines.

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Chloranthus elatior Link Chloranthaceae

Santoso¹

2021

Ethnobotany of Mountain Regions

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Terpenes from Mikania aff. jeffreyi (Asteraceae)

Cited by 8 publications

References 0 publications

Communic Acids: Occurrence, Properties and Use as Chirons for the Synthesis of Bioactive Compounds

Communic Acids: Occurrence, Properties and Use as Chirons for the Synthesis of Bioactive Compounds

Structural Characterization and Biological Evaluation of 18‐Nor‐ent‐labdane Diterpenoids from Grazielia gaudichaudeana

Chloranthus elatior Link Chloranthaceae

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