Terpenes

Xavier, Virginie; Spréa, Rafael Mascoloti; Finimundy, Tiane C.; Heleno, Sandrina A.; Amaral, Joana S.; Barros, Lillian; Ferreira, Isabel C.F.R.

doi:10.1007/978-3-031-18587-8_5

Cited by 5 publications

(4 citation statements)

References 256 publications

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“…Comparing the oils from the two hydrodistillation methods, in general, the one obtained through MADH exhibited lower GI 50 values for tumor cell lines and higher GI 50 values for non-tumor cell lines, although no significant differences (p > 0.05) were observed for the NCI-H460 and VERO cell lines. Previous studies reported antiproliferative and antitumor properties for different individual terpenes, which may be related to the activity observed in this work [29]. Citral isomers (neral and geranial) were shown to induce apoptosis in chronic lymphoid leukemia by activation of caspase-3 [30,31].…”

Section: Cytotoxicity and Anti-inflammatory Activitysupporting

confidence: 76%

Volatile Compounds and Biological Activity of the Essential Oil of Aloysia citrodora Paláu: Comparison of Hydrodistillation and Microwave-Assisted Hydrodistillation

et al. 2023

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Aromatic plants are a remarkable source of natural products. Aloysia citrodora Paláu (Verbenaceae), commonly known as lemon verbena, is a relevant source of essential oils with potential applications due to its lemony scent and bioactive properties. Studies carried out on this species have focused on the volatile composition of the essential oil obtained by Clevenger hydrodistillation (CHD), with little information available on alternative extraction methodologies or the biological properties of the oil. Therefore, this work aimed to compare the volatile composition, antioxidant activity, cytotoxicity, anti-inflammatory and antibacterial activities of the essential oil extracted by conventional hydrodistillation by Clevenger (CHD) and Microwave-Assisted Hydrodistillation (MAHD). Significant differences (p < 0.05) were observed for some compounds, including the two major ones, geranial (18.7–21.1%) and neral (15.3–16.2%). Better antioxidant activity was exhibited by the MAHD essential oil in DPPH radical scavenging and reducing power assays, while no differences were observed in the cellular antioxidant assay. The MADH essential oil also presented higher inhibition against four tumoral cell lines and exhibited lower cytotoxicity in non-tumoral cells as compared with Clevenger-extracted essential oil. In contrast, the latter showed higher anti-inflammatory activity. Both essential oils were able to inhibit the growth of eleven out of the fifteen bacterial strains tested.

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Section: Cytotoxicity and Anti-inflammatory Activitysupporting

confidence: 76%

Volatile Compounds and Biological Activity of the Essential Oil of Aloysia citrodora Paláu: Comparison of Hydrodistillation and Microwave-Assisted Hydrodistillation

et al. 2023

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“…Los alcaloides y terpenos detectados en L. humile son un carácter común de la familia Solanaceae y del género Lycium (Qian et al, 2017), encontrándose este tipo de metabolitos con potencial medicinal, alimenticio y para la industria cosmestica (Heinrich et al, 2021;Xavier et al, 2023) en L. barbarum (Gonçalves et al, 2018), L. chinense Mill. (Youn et al, 2013) y L. europaeum L. (Bendjedou et al, 2021), entre otros.…”

Section: Discusión Y Conclusionunclassified

Morfo-anatomía e histoquímica de órganos vegetativos de Lycium humile (Solanaceae): rasgos adaptativos a humedales salinos de altura

Leal,

Mercado,

Cuello

et al. 2023

Darwiniana, nueva serie

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Lycium humile Phil., is an extreme halophyte plant, endemic to Argentina, Bolivia, and Chile, which grows between 2000 and 4000 m a.s.l. in saline wetlands environments. The aim of this work is to identify morpho-anatomical and histochemical adaptive characteristics of the vegetative organs of L. humile linked to its tolerance to extreme environments of high altitude saline wetlands, in order to evaluate its potential as source of metabolites with commercial value or as source of resistance genes related to abiotic stress tolerance. To carry out the analysis, during the period of February 2018, samples were obtained from plants belonging to 4 populations of the species (5 individuals per population) located at the departments of Antofagasta de la Sierra, Santa María and Ambato, province of Catamarca, Argentina. Leaf and stems were studied using histochemical tests, conventional histological preparations and optical microscopy. Different foliar tissues were analyzed by scanning electron microscopy coupled to elemental X-ray diffraction spectroscopy (EDS). The leaves and stems of the analyzed populations showed uniform anatomical and histochemical features. It was stated for the first time that the succulence of the leaf is reached by the folding of the tissues evidenced in a tridimensional venation pattern. The presence of isolateral-radial mesophyll and aquifer parenchyma is highlighted as a unique feature characteristic for the species. The glandular trichomes and palisade parenchyma revealed complex contents of phenols, flavonoids, proteins, lipids, terpenes, and alkaloids; while the outer layer of the cuticles presented phenolic, terpenic and lipidic deposits. The EDS analysis showed crystalliferous idioblasts with high contents of Ca2+ and Na+. The stems exhibited hypodermis and air chambers formed in the cortical and medullary layers. These anatomical and histochemical characteristics of L. humile represent adaptive traits to saline high-altitude wetland environments. Its functionality in relation to the environment and its potential as source of resistance genes and metabolites interesting for the cosmetic and pharmaceutical industries are discussed.

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“…Essential oils (EOs) are complex mixtures mainly composed of several terpenes, commonly used as natural ingredients [ 5 ]. Essential oils of common spices, such as clove, cinnamon, basil, nutmeg, thyme, and oregano, are considered in the category Generally Recognized as Safe (GRAS) by the Food and Drug Administration (FDA).…”

Section: Introductionmentioning

confidence: 99%

Chemical and Bioactive Evaluation of Essential Oils from Edible and Aromatic Mediterranean Lamiaceae Plants

Spréa,

Caleja,

Finimundy

et al. 2024

Molecules

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The Lamiaceae family, which includes several well-known aromatic plants, is scientifically relevant due to its essential oils (EOs). In this work, four EOs from Mediterranean species, namely Origanum vulgare L., Rosmarinus officinalis L., Salvia officinalis L., and Thymus vulgaris L., were evaluated for their volatile profiles and the biological activity in vitro to assess their potential use in the food and cosmetic sector. GC/MS analysis revealed dominant compounds, such as carvacrol, thymol, and eucalyptol. Regarding biological action, the samples exhibited antioxidant, cytotoxic, anti-inflammatory, antimicrobial, and antifungal activities, with O. vulgare and T. officinalis standing out. T. vulgaris showed the lowest EC50 in the reducing power assay, and O. vulgare had the lowest EC50 in the DPPH assay. Most EOs also displayed excellent anti-inflammatory responses and antifungal properties, with O. vulgare and T. vulgaris also demonstrating antibacterial activity. All EOs from Mediterranean species showed cytotoxicity against tumoral cell lines. Overall, the selected EOs stood out for their interesting bioactivities, with the obtained results underscoring their potential as natural preservatives and bioactive agents in various industrial applications, including food, pharmaceuticals, and cosmetics.

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Terpenes

Cited by 5 publications

References 256 publications

Volatile Compounds and Biological Activity of the Essential Oil of Aloysia citrodora Paláu: Comparison of Hydrodistillation and Microwave-Assisted Hydrodistillation

Volatile Compounds and Biological Activity of the Essential Oil of Aloysia citrodora Paláu: Comparison of Hydrodistillation and Microwave-Assisted Hydrodistillation

Morfo-anatomía e histoquímica de órganos vegetativos de Lycium humile (Solanaceae): rasgos adaptativos a humedales salinos de altura

Chemical and Bioactive Evaluation of Essential Oils from Edible and Aromatic Mediterranean Lamiaceae Plants

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