Terminology of developmental abnormalities in common laboratory mammals (version 1)

Wise, L. David; Beck, Susan; Beltrame, D; Beyer, Bruce K.; Chahoud, Ibrahim; Clark, Ruth; Druga, Alice; Feuston, Maureen H.; Guittin, Pierre; Henwood, Susan; Kimmel, Carole A.; Lindström, Pia; Palmer, Andrew K.; Petrere, Judith A.; Solomon, Howard M.; Yasuda, Mineo; York, Raymond G.

doi:10.1002/(sici)1096-9926(199704)55:4<249::aid-tera5>3.0.co;2-w

Cited by 158 publications

(60 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…More work needs to be done on the developing tadpole, in the field and in the laboratory, to better elucidate the range, frequency, character and causes of anuran malformations. Descriptions of frog malformations in this report are based on terminology used in human literature (Bolande, 1979;Robbins, et al, 1989), developmental biology (O'Rahilly, et al, 1996Carlson, 1994;Gilbert, 1997), and teratology (Wise, et al, 1997). Many of these terms were originally used to describe abnormalities in the mammalian fetus at birth.…”

mentioning

confidence: 99%

A Practical Guide for the Study of Malformed Amphibians and Their Causes

Lunde¹,

Johnson²

2012

Journal of Herpetology

View full text Add to dashboard Cite

mentioning

confidence: 99%

A Practical Guide for the Study of Malformed Amphibians and Their Causes

Lunde¹,

Johnson²

2012

Journal of Herpetology

View full text Add to dashboard Cite

“…External morphological findings are classified as developmental malformations and have been used by researchers in an internationally developed glossary for structural developmental abnormalities in laboratory mammals. [15] Implantation sites were viewed by the application of a drop of ammonium sulphide (NH4)2S solution on the animal's placenta and left for a day to view dark implantation rings signifying the number of implantation sites. The ovaries were excised and fixed in Bouin's fluid for corpora lutea count.…”

Section: Methodsmentioning

confidence: 99%

A comparative study on the embryo-fetal development in rabbits after artificial insemination

Obasi¹,

Lambe²,

Gbadamosi³

et al. 2016

Anatomy

View full text Add to dashboard Cite

Objectives: Artificial insemination (AI) is the introduction of spermatozoa into a female's uterus or cervix for the purpose of achieving pregnancy. It is a fertility treatment for humans, in animal breeding and embryo-fetal developmental studies. This study investigated the embryo-fetal development in the rabbit via artificial insemination by evaluating the litter size, reproductive data and external morphological abnormalities after insemination. Methods:Ten adult female and three male rabbits weighing 1.8 kg and 2 kg, respectively were used. Group A served as the natural mating, while Group B served as the AI group, and the males served as semen donors. On day 28 of gestation, does were subjected to caesarean section. The ovaries and uteri were removed and examined for the number of corpora lutea and the status of all implantation. Results:Results showed a significant increase in fetal weight, total fetal number, total resorption sites, number of implantation and total number of live foetuses (p<0.05), while there was no significant increase in parameters like average fetal weight, placenta weight, uterine gravid weight, number of corpora lutea and sex ratio in Group B compared to Group A (p>0.05). A conception rate of 100% was observed in Group A compared to Group B with 80% conception rate. External examination carried out on the foetuses revealed no external abnormalities in both groups. Conclusion:The results of this study show the clear advantages in the use of rabbits for AI in terms of embryo-fetal developmental studies.

show abstract

“…The Committee on International Harmonization of Nomenclature in Developmental Toxicology of the International Federation of Teratology Societies has developed and published a glossary of internationally accepted common nomenclature to use when describing observations of fetal and neonatal morphology (Wise et al, 1997). The purpose of this effort was to advance the harmonization of terminology and to reduce confusion and ambiguity in the description of developmental effects, particularly in submissions to regulatory agencies worldwide.…”

Section: Birth Defects and Malformationsmentioning

confidence: 99%

Expressing urine from a gel disposable diaper for biomonitoring using phthalates as an example

Liu

Xia

Guo

et al. 2012

J Expo Sci Environ Epidemiol

View full text Add to dashboard Cite

The urinary metabolites of phthalates are well-accepted exposure biomarkers for adults and children older than 6 years but are not commonly used for infants owing to non-convenient sampling. In the light of this situation, a novel sampling method based on monitoring the urine expressed from the gel diaper was developed. The urine was expressed from the gel absorbent after mixing the absorbent with CaCl2 and then collected by a laboratory-made device; the urinary phthalate metabolites were extracted and cleaned using a solid-phase extraction (SPE) column and analyzed with high-performance liquid chromatography-electrospray ionization-tandem mass spectrometry / mass spectrometry. To evaluate the method's feasibility, the following factors were investigated: the proportion of CaCl2 to gel absorbent, the urination volume variation and the target compounds' deposition bias in the diaper, the matrix blank of the different diaper brands, the storage stabilities and the recoveries of creatinine and phthalate metabolites in the expressed urine. Mono-methyl phthalate, mono-ethyl phthalate, mono-butyl phthalate, mono-benzyl phthalate, mono-2-ethylhexyl phthalate and mono-2-ethyl-5-oxohexyl phthalate were involved. 70-80% of the urine can be expressed from the diaper, and the expressed spiking recoveries and the limit of detection of mono-phthalates ranged from 88.5-115% and 0.21-0.50 ng/ml. The method was applied to measure phthalate metabolites in 65 gel diaper samples from 15 infants, and the pilot data suggests the infants are commonly exposed to phthalates. In summary, the method for monitoring of infant exposure to phthalates is sound and validated, and the potential health effects from the vulnerable infants' exposure to phthalates should be concerned.39th Scientific Research Foundation for the Returned Overseas Chinese Scholars (SRF for ROCS); Hundred Talent Program of Chinese Academy of Sciences (CAS); CAS/SAFEA International Partnership Program for Creative Research Teams [KZCX2-YW-T08

show abstract

Terminology of developmental abnormalities in common laboratory mammals (version 1)

Cited by 158 publications

References 0 publications

A Practical Guide for the Study of Malformed Amphibians and Their Causes

A Practical Guide for the Study of Malformed Amphibians and Their Causes

A comparative study on the embryo-fetal development in rabbits after artificial insemination

Expressing urine from a gel disposable diaper for biomonitoring using phthalates as an example

Contact Info

Product

Resources

About