Termination of pregnancy with Utus paste: report of a fatal case.

Abstract

BRITISH MEDICAL JOURNAL 15 FEBRUARY 1975 375 Technetium-99m-labelled pertechnetate is 90% bound to intravascular proteins and diffuses readily to extravascular spaces (Hays and Green, 1972). In normal subjects an equilibrium is reached in muscles 6-8 minutes between intravascular and extravascular pertechnetate. This time was more than doubled in our patient at the beginning of the disease, most probably because of the inflammatory processes involved in the angiitis, but it returned to normal under treatment.Furthermore, the scintigraphic changes correlated well with the clinical state and the changes in the biological values. The scan pattern and the delay in the equilibrium of the curve were still abnormal when the second biopsy was normal though one could infer from the clinical state and the E.S.R. that the disease was still active. After 13 weeks the only abnormalities were a raised E.S.R. and the scan pattern.Whether the appearance of the scan is pathognomic for periarteritis nodosa, as stated by Mintz et al. (1970), remains to be proved, but we feel that the combination of dynamic studies and scintigraphy provided a valuable and objective means of evaluating the extent of this disease and its response to treatment. The possibilities offered by this simple method in other collagen and muscle diseases are under investigation.We thank Mr. A. Dobbeleer for technical help and Professor S. Orloff for referring normal controls.

Toxicology and teratology of the active ingredients of professional therapy MuscleCare products during pregnancy and lactation: a systematic review

“… • It is not associated with increased risks of birth defects. [ 21 , 72 - 76 ] • It is toxic to mucous membranes and to kidneys, liver, and central nervous system. Animal • Topically, it is safe.…”

“…Thymol was not associated with increased incidence of birth defects based on 52 pregnancies exposed in the first trimester of pregnancy [ 21 ]. Although thymol was used previously as part of an abortifacient paste to induce the abortion [ 73 - 75 ], only one fatality was reported with the paste use [ 76 ].…”