Terminalia chebula Retz.

Khare, C.P.

doi:10.1007/978-0-387-70638-2_1616

Cited by 2 publications

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“…The medicinal plant Terminalia chebula [1][2][3][4][5][6] , belonging to the family Combretaceae commonly known as Black or Chebulic Myrobalan also termed as King of Medicines is used to cure all kind of the diseases. This plant is abundantly available in remote areas of Yeleswaram and Rampachodavaram forest areas.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of analgesic and anti-inflammatory activities of ethanolic fruit extract of Terminalia chebula

K. RAVISHANKAR,

K. GNANESWARI,

S. THIRUMALA DEVI

2024

GSC Adv. Res. Rev.

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Analgesic and Anti-inflammatory activities of ethanolic fruit extract of Terminalia chebula was evaluated using tail-flick method, eddy’s hot plate method, acetic acid induced writhing responses and in-vivo anti-inflammatory property was determined using carrageenan rat paw edema. The ethanolic fruit extract of Terminalia chebula at different concentrations significantly inhibited the nociception in comparision with different standard drugs that showed anti-nociception. The test extract also reduced the edema induced in rats using carrageenan paw edema method as compared with the standard drug Diclofenac sodium 10mg/kg. The results obtained in this research study found to be very significant when compared to standard reference drug.

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Section: Introductionmentioning

confidence: 99%

Evaluation of analgesic and anti-inflammatory activities of ethanolic fruit extract of Terminalia chebula

K. RAVISHANKAR,

K. GNANESWARI,

S. THIRUMALA DEVI

2024

GSC Adv. Res. Rev.

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“…And the study compares the drug phytoconstituents before and after the rectification process to understand the phytochemical changes by physicochemical and instrumental analysis. Thus the present study was an attempt to establish the evaluation of Halela as a medicinal agent against various human diseases such as tumors, intermittent fever, rheumatism, paralysis, memory loss, diabetes, neurological problems, hepatomegaly, and constipation 18 .…”

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confidence: 99%

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2022

IJPSR

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Background: Halela (Terminalia chebula Retz) is one of the constituents in the well-known Unani compound medicine Itriphal, which has been used for thousands of years to treat a variety of ailments. In order to improve the therapeutic activity of the drug, the present study adapted the process of Tadbeer / Mudabbar (rectification/purification) which is based on the concept of Islah-e-Advia. This process thus helps in making the drug effective, safe, and specific, or minimizing undesirable characteristics by acting on the drug's constituents without compromising its medicinal value through various methods (rectification process). Objectives: To further grasp the significance of the notion of Islah-e-Advia, before and after Halela Mudabbar (rectification), a comparative analysis was conducted. Methods: Mudabbar was done by roasting dry Halela powder with Almond oil for 7-10 minutes on a low flame on standard cooking gas. Physico-chemical and quantitative HPLC examinations of gallic acid, ellagic acid, chebulagic acid, and chebulinic acid were performed with Halela before and after the Mudabbar procedure. Results: Quantitative HPLC analysis of gallic acid, ellagic acid, chebulagic acid, and chebulinic acid was increased to 0.6, 5.7, 3.8, and 0.6 mg/mL in post mudabbar halela (PMH) as compared to 0.5, 4.8, 3.5, and 0.4 mg/mL in pre halela (PH), suggesting a significant increase in tannin content in PMH. Conclusion:The results clearly show alterations in PMH, proving the notion of Islah-e-Advia and likely enhancing the drug's activity. Standards for pre and post mudabbar Halela were established for future reference. This study may provide an incentive for proper evaluation of the plant as a medicinal agent against human diseases and also to bridge the lacunae in the existing literature and future scope, which may offer immense opportunity for researchers engaged in validating the traditional claims and development of safe and effective botanical medicine.

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Terminalia chebula Retz.

Cited by 2 publications

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Evaluation of analgesic and anti-inflammatory activities of ethanolic fruit extract of Terminalia chebula

Evaluation of analgesic and anti-inflammatory activities of ethanolic fruit extract of Terminalia chebula

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