Terminal innervation of female genitalia, cutaneous sensory receptors of the epithelium of the labia minora

Abstract

FNEs, Meissner's corpuscles and Pacinian corpuscles are present in the female labia minora and exhibit characteristic staining patterns.

Hyperplastic sensory corpuscles in nevus sebaceus of labia minora pudendi. A case report

“…Malinovský et al described several types of encapsulated and non‐capsulated corpuscles in the human vulva, considering only a minority of the non‐capsulated corpuscles as genuinely reminiscent of cutaneous Meissner corpuscles. Nevertheless, Schober et al failed to identify such diverse types of corpuscles, but also identified pseudo‐Meissner corpuscles . Our present results basically agree with previous studies reporting the occurrence of different morphotypes of sensory corpuscles, including non‐capsulated Meissner‐like and partially‐capsulated glomerular corpuscles, in human female genital skin .…”

“…Nevertheless, Schober et al failed to identify such diverse types of corpuscles, but also identified pseudo‐Meissner corpuscles . Our present results basically agree with previous studies reporting the occurrence of different morphotypes of sensory corpuscles, including non‐capsulated Meissner‐like and partially‐capsulated glomerular corpuscles, in human female genital skin . Nevertheless, the large size, sometimes angulated morphology and irregular intracorpuscular axonal course in the Meissner‐like corpuscles suggests that they are influenced by the hamartomatous lesion.…”

“…Deep sensory corpuscles display a regular arrangement of the axon (with several parallel segments) and glial cells, and thus can be identified as genuine glomerular or genital sensory corpuscles (Figure A and B).…”

Time-Frequency Analysis of Increases in Vaginal Blood Perfusion Elicited by Long-Duration Pudendal Neuromodulation in Anesthetized Rats

“…Currently, there are no effective treatment options specifically targeting the genital, rather than psychological, component of female sexual arousal . In part, this is due to the challenge of studying the mechanisms of the physiological components of female arousal, an area of research that is still developing . A treatment for genital arousal dysfunction may also affect other components of sexual dysfunction, and thus would have wide applicability across FSD subtypes.…”

The clinical anatomy of dyspareunia: A review

“…The nerve branches to the vulva also possess A delta and C fibers that serve as nociceptors (Steege and Zolnoun, ). The labia minora also possesses some terminal sensory fibers that might play a role in pain perception (Schober et al, ).…”