SUMMARYHenoch-Schönlein purpura (HSP) is caused by deposition of IgA-containing immune complexes within the blood vessels. HSP mostly occurs in children and is less common in adults. In addition to palpable purpura, arthritis or arthralgia, renal disease and abdominal pain, gastrointestinal symptoms occur in 50% of children. These can be caused by gastrointestinal hemorrhage, bowel ischemia and necrosis, intussusception, and bowel perforation. In adults, intussusception is less frequent than in children. We report a 42-year-old woman referred to our hospital with acute abdominal pain. After laboratory and radiologic examinations, laparatomy was performed which revealed rectal perforation due to HSP. HSP is a multisystem disorder. Abdominal pain in patients with HSP may herald a serious gastrointestinal problem also in adult patients.
Key words:Henoch-Schönlein purpura; Bowel perforation; Abdominal pain; Rectal perforation. Reumatismo, 2017; 69 (3): 131-133 n INTRODUCTION H enoch-Schönlein purpura (HSP), also called IgA vasculitis, is caused by deposition of IgA-containing immune complexes within the blood vessels (1) and its characteristic finding is leukocytoclastic vasculitis. HSP mostly occurs in children between the ages of 3 and 15 years (2) and is less common in adults (3). The incidence of 3.4 to 14.3 per million was reported for HSP in adults (4). HSP manifestations in children include palpable purpura, arthritis or arthralgia, renal disease and abdominal pain (5). Gastrointestinal symptoms like nausea, vomiting, abdominal pain, and transient paralytic ileus occur in 50% of the children and the findings are: gastrointestinal hemorrhage; bowel ischemia and necrosis; intussusception, and bowel perforation (6). In adults, in addition to the above-mentioned manifestations, there are two main differences: intussusception is rare and the risk of renal disease is increased (7). The diagnosis of HSP is usually based on clinical manifestations, especially palpable purpura in the lower extremities and a biopsy of the involved organ (e.g., skin or kidney) in those who have unusual presentations. There is no specific diagnostic laboratory test (8). Imaging is commonly performed on patients with abdominal pain. Abdominal radiography may show dilatation of the bowel loops; it may demonstrate peritoneal fluid, hematomas, intussusception and an increased bowel wall thickness (9). We report a rare case of rectal perforation due to HSP in a 42-year-old woman.
n CASE REPORTA 42-year-old woman with chief complaint of abdominal pain, was referred to Rasool-e-Akram hospital in February 2015. Her pain had started gradually a week before in the hypogastric region re- We report a 42-year-old woman referred to our hospital with acute abdominal pain. After laboratory and radio logic examinations, laparatomy was performed which revealed rectal perforation due to HSP. risk of renal disease is increased (7). The u s e blood vessels. HSP mostly occurs in children and is less common in adults. In addition to palpable purpura, u s e...