Terapia de oxígeno hiperbárico complementaria al desbridamiento en el control de la gangrena de Fournier: utilidad de la puntuación de un índice de severidad en la predicción de la gravedad de la enfermedad y la supervivencia del paciente

Janane, A.; Hajji, F.; Ismail, T. Ould; Chafiqui, J.; Ghadouane, M.; Ameur, A.; Abbar, M.; Albouzidi, A.

doi:10.1016/j.acuro.2011.01.019

Cited by 25 publications

(11 citation statements)

References 18 publications

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“…Altarac et al .,[1] found FGSI score to be significantly higher among non-survivors (11 vs. 6, P > 0.0001). On the other hand, Janane et al .,[24] found that median admission FGSI scores for survivors and non-survivors were not significantly different (2.1 ± 2.0 vs. 4.2 ± 3.8, P = 0.331). Tuncel et al .,[22] did not find a significant association of FGSI to mortality.…”

Section: Discussionmentioning

confidence: 95%

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Prospective evaluation of risk factors for mortality in patients of Fournier′s gangrene: A single center experience

Vyas¹,

Kumar²,

Bhandari³

et al. 2013

Indian J Urol

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Introduction:Fournier's gangrene is an aggressive disease with high morbidity and mortality. The aim of this study was to assess risk factors associated with mortality among patients of Fournier's gangrene.Materials and Methods:Between May 2011 and September 2012, all patients of Fournier's gangrene treated at our center were included in the study. All patients underwent emergency surgical debridement and received broad spectrum intravenous antibiotics. Their baseline characteristics, treatment, and follow-up data were recorded and analyzed.Results:A total of 30 patients were included in the study. Of these, six patients (20%) died during the treatment. Age <55 years, total leukocyte count <15000 cumm, extent of the area involved, septic shock at admission, visual analog scale (VAS) <7 at admission, and Fournier gangrene severity index (FGSI) score <8 at admission were significantly associated with increased mortality.Conclusion:In patients of Fournier's gangrene, increased age, total leukocyte count, extent of the area involved, septic shock at admission, VAS score, and FGSI score at admission have a significant association with mortality.

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Section: Discussionmentioning

confidence: 95%

“…Janane et al .,[24] found that the extent of body surface area involved by the disease process has a significant impact on the mortality ( P = 0.001). Other studies also found its significant association with mortality.…”

Section: Discussionmentioning

confidence: 99%

Prospective evaluation of risk factors for mortality in patients of Fournier′s gangrene: A single center experience

Vyas¹,

Kumar²,

Bhandari³

et al. 2013

Indian J Urol

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“…Other studies have shown that the FGSI is unable to predict disease severity and survival. [30][31][32] Tuncel et al [20] concluded in a subsequent study that addition of age and involved surface area parameters was necessary to predict mortality.…”

Section: Discussionmentioning

confidence: 99%

The presentation, management and outcomes of Fournier’s gangrene at a tertiary urology referral centre in South Africa

Elsaket

Maharajh²,

Urry

2018

S Afr Med J

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In a resource-constrained environment such as SA, outcome prediction is necessary to enable resource allocation. Patients with an FGSI >9 have a high risk of mortality and will benefit from ICU care. The combination of FGSI >9, requirement for organ support and extension beyond the perineum is associated with a very high risk of mortality and may be useful as an exclusion criterion when allocating scarce resources.

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“…Despite appropriate treatment, mortality rates remain high, up to 67% [14], even if a recent article by Janane and coworkers reported, in a case series of 70 patients treated with both VAC therapy and hyperbaric oxygen therapy, a very low mortality rate (11.4%), failing also to confirm the predictive value of Fournier's gangrene severity score index [15]. Unfortunately, this report is available only in Spanish, thus, important details about this wide sample are unknown for many readers.…”

Section: Discussionmentioning

confidence: 99%

Treatment of Fournier's Gangrene with Combination of Vacuum-Assisted Closure Therapy, Hyperbaric Oxygen Therapy, and Protective Colostomy

Zagli

Cianchi

Degl'Innocenti

et al. 2011

Case Reports in Anesthesiology

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Fournier's gangrene is a rare process which affects soft tissue in the genital and perirectal area. It can also progress to all different stages of sepsis, and abdominal compartment syndrome can be one of its complications. Two patients in septic shock due to Fournier gangrene were admitted to the Intensive Care Unit of Emergency Department. In both cases, infection started from the scrotum and the necrosis quickly involved genitals, perineal, and inguinal regions. Patients were treated with surgical debridement, protective colostomy, hyperbaric oxygen therapy, and broad-spectrum antibacterial chemotherapy. Vacuum-assisted closure (VAC) therapy was applied to the wound with the aim to clean, decontaminate, and avoid abdominal compartmental syndrome development. Both patients survived and were discharged from Intensive Care Unit after hyperbaric oxygen therapy cycles and abdominal closure.

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Terapia de oxígeno hiperbárico complementaria al desbridamiento en el control de la gangrena de Fournier: utilidad de la puntuación de un índice de severidad en la predicción de la gravedad de la enfermedad y la supervivencia del paciente

Cited by 25 publications

References 18 publications

Prospective evaluation of risk factors for mortality in patients of Fournier′s gangrene: A single center experience

Prospective evaluation of risk factors for mortality in patients of Fournier′s gangrene: A single center experience

The presentation, management and outcomes of Fournier’s gangrene at a tertiary urology referral centre in South Africa

Treatment of Fournier's Gangrene with Combination of Vacuum-Assisted Closure Therapy, Hyperbaric Oxygen Therapy, and Protective Colostomy

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