“…Data on recurrence and follow-up times pertaining to 6,366 patients treated for PSD by limited excision PSD treatment were extracted from 71 additional non-RCTs 52 , 61 , 69 , 72 , 73 , 75 , 81 , 83 , 88 , 94 , 106 , 114 , 119 , 121 , 124 , 125 , 131 , 140 , 142 , 144 , 149 , 160 , 208 , 221 , 226 , 248 , 249 , 261 , 285 , 293 , 295 , 319 , 321 , 322 , 400 , 410 , 416 , 536 , 609 , 625 – 656 . Among these patients, a recurrence of 5.0% (95% CI 4.3–5.6%) was observed in patients at 12 months, 6.8% (95% CI 6.0–7.7%) at 24 months, 16.2% (95% CI 14.3–18.2%) at 60 months, and 34.0% (95% CI 26.3–41.6%) at 120 months (Supplementary Fig.…”