Tensile Strength Comparison of Small Intestinal Submucosa Body Wall Repair

Ko, Rainier; Kazacos, Evelyn A.; Snyder, Scott A.; Ernst, David M.J.; Lantz, Gary C.

doi:10.1016/j.jss.2006.02.007

Cited by 35 publications

(29 citation statements)

References 43 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…While in underlay technique the position of the implant behind the rectus muscles minimize hernia recurrence rates. The same explanation was obtained by Reilingh et al [15] and Rainier et al [16].…”

Section: Discussionsupporting

confidence: 86%

“…This type of failure indicates a lower tensile strength of the muscle and fascia than at the repair site [16,21]. The differences among overall mean values of load at failure and healing tensile strength of prolene mesh and GTV implants were not statistically signifi cant at each time interval; these results suggested that the implanted materials were suffi ciently strong to maintain abdominal wall integrity.…”

Section: Discussionmentioning

confidence: 95%

See 1 more Smart Citation

Repair of Large Abdominal Wall Defect Using Glycerolized Bovine Tunica Vaginalis and Prolene Mesh Implants in Dogs

Abouelnasr¹

2017

Int J Vet Sci Res

View full text Add to dashboard Cite

The repair of large abdominal defects remains a complex surgical problem of insuffi cient autogenous tissue for adequate reconstruction. The aim of the present study was to evaluate the uses of polypropylene mesh with glycerolized tunica vaginalis (GTV) for repairing abdominal wall defects in dogs using either inlay or underlay technique of implatations. Full thickness (all the layers of muscles except the skin) abdominal wall defects (6 x 10 cm) were created in 24 healthy mongrel dogs allocated into two main equal group (n= 12 each) according to the type of the prosthetic material used. Each group is subdivided into two subgroup (n= 6 each).The present study indicated that, GTV Patches are considered to be a successful alternative for reinforcement and repair of large abdominal wall defects than prolene mesh based on postmortem fi ndings, biomechanical analysis and histopathological examination.

show abstract

Section: Discussionsupporting

confidence: 86%

Section: Discussionmentioning

confidence: 95%

Repair of Large Abdominal Wall Defect Using Glycerolized Bovine Tunica Vaginalis and Prolene Mesh Implants in Dogs

Abouelnasr¹

2017

Int J Vet Sci Res

View full text Add to dashboard Cite

show abstract

“…The anatomic position of the mesh placement has an impact on tissue incorporation, tissue reaction, and tensile strength of the abdominal wall. [6][7][8] These factors are important regarding IH recurrence and postoperative complications.…”

Section: Introductionmentioning

confidence: 99%

Open mesh repair, is still a standard technique for incisional hernia: a comparision study between sublay and onlay technique in the era of laparoscopy

et al. 2018

View full text Add to dashboard Cite

Background: Incisional hernia (IH) remains a very frequent postoperative complication and common hernias in middle aged population more commonly in females. The two techniques most frequently used are the onlay repair and sublay repair. Various studies have been conducted to compare the advantages and disadvantages of sublay and onlay mesh repair in incisional hernia and the superiority of sublay mesh repair. These studies whether they hold good for the population is a pertinent question. In view of this, author need to study the appropriate surgical techniques sublay versus onlay repair in the set up.Methods: Author conducted randomized comparative study of 100 patients having incisional hernia admitted to various surgical units of SNMC and HSK Hospital, Bagalkot during the period December 2014 to June 2016.Results: In present study of 100 cases, females have more incidence of incisional hernias than males. In onlay technique seroma formation was found in 72% of patients postoperatively and 4% in sublay technique. Surgical site infection (SSIN) was noticed in 8% of sublay technique whereas 12% in onlay technique. There is no recurrence in sublay group whereas onlay had 12% recurrence.Conclusions: Sublay technique is superior to onlay concerning the hospital stay, complications and recurrence.

show abstract

“…[22][23][24][25] Various studies have been performed to prove the feasibility of SIS as a tissue engineering scaffold in animal models of rats, dogs, and pigs, and even human patients. [25][26][27][28] Different types of seed cells have been used for repairing abdominal wall defects, including skeletal muscle, skin fibroblasts, and bone marrow stem cells. 21,25,29 However, there have been no published reports on the use of tenocytes to engineer aponeurosis for potential applications in abdominal wall reconstruction.…”

Section: Introductionmentioning

confidence: 99%

Reconstruction of Abdominal Wall Musculofascial Defects with Small Intestinal Submucosa Scaffolds Seeded with Tenocytes in Rats

Song

Peng

Liu

et al. 2013

Tissue Engineering Part A

View full text Add to dashboard Cite

The repair of abdominal wall defects following surgery remains a difficult challenge. Although multiple methods have been described to restore the integrity of the abdominal wall, there is no clear consensus on the ideal material for reconstruction. This study explored the feasibility of in vivo reconstruction of a rat model of an abdominal wall defect with a composite scaffold of tenocytes and porcine small intestinal submucosa (SIS). In the current study, we created a 2 · 1.5 cm abdominal wall defect in the anterolateral abdominal wall of SpragueDawley rats, which were assigned into three groups: the cell-SIS construct group, the cell-free SIS scaffold group, and the abdominal wall defect group. Tenocytes were obtained from the tendons of rat limbs. After isolation and expansion, cells (2 · 10 7 /mL) were seeded onto the three-layer SIS scaffolds and cultured in vitro for 5 days. Cell-SIS constructs or cell-free constructs were implanted to repair the abdominal wall defects. The results showed that the tenocytes could grow on the SIS scaffold and secreted corresponding matrices. In addition, both scaffolds could repair the abdominal wall defects with no hernia recurrence. In comparison to the cell-free SIS scaffold, the composite scaffold exhibited increased vascular regeneration and mechanical strength. Furthermore, following increased time in vivo, the mechanical strength of the composite scaffold became stronger. The results indicate that the composite scaffold can provide increased mechanical strength that may be suitable for repairing abdominal wall defects.

show abstract

Tensile Strength Comparison of Small Intestinal Submucosa Body Wall Repair

Cited by 35 publications

References 43 publications

Repair of Large Abdominal Wall Defect Using Glycerolized Bovine Tunica Vaginalis and Prolene Mesh Implants in Dogs

Repair of Large Abdominal Wall Defect Using Glycerolized Bovine Tunica Vaginalis and Prolene Mesh Implants in Dogs

Open mesh repair, is still a standard technique for incisional hernia: a comparision study between sublay and onlay technique in the era of laparoscopy

Reconstruction of Abdominal Wall Musculofascial Defects with Small Intestinal Submucosa Scaffolds Seeded with Tenocytes in Rats

Contact Info

Product

Resources

About