Tenofovir-Induced Renal Dysfunction Among HIV-Infected Patients: A Systematic Review
Yogamba M Shivakumar,
Eshwar Burra,
Kamran Shahid
et al.
Abstract:Tenofovir disoproxil fumarate (TDF) is an antiretroviral drug widely used as part of antiretroviral therapy (ART) to treat human immunodeficiency virus (HIV-1) infection. Negative effects of tenofovir include impaired kidney function, especially with long-term use.
In studies conducted among HIV-positive individuals, we found evidence of extensive kidney damage associated with TDF use. Despite the therapeutic importance of this consequence, its continued use in ART regimens was not contraindicated. … Show more
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