Tendon Injuries

Weise, K.

doi:10.1007/978-3-540-88124-7_16

Cited by 2 publications

(1 citation statement)

References 10 publications

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“…musculotendinous transfer) [105][106][107]. This procedure causes morbidity at the harvest site and often leads to suboptimal results [108,109]. There is an increasing need to supply meaningful volumes of biocompatible muscle tissue that mimic the structure and function of the native counterpart for the treatment of muscle injuries occurring due to sports, aging, and disease like myosarcoma or degenerative muscle diseases.…”

Section: Introductionmentioning

confidence: 99%

Recent advances in 3D bioprinting of musculoskeletal tissues

et al. 2021

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The musculoskeletal system is essential for maintaining posture, protecting organs, facilitating locomotion, and regulating various cellular and metabolic functions. Injury to this system due to trauma or wear is common, and severe damage may require surgery to restore function and prevent further harm. Autografts are the current gold standard for the replacement of lost or damaged tissues. However, these grafts are constrained by limited supply and donor site morbidity. Allografts, xenografts, and alloplastic materials represent viable alternatives, but each of these methods also has its own problems and limitations. Technological advances in three-dimensional (3D) printing and its biomedical adaptation, 3D bioprinting, have the potential to provide viable, autologous tissue-like constructs that can be used to repair musculoskeletal defects. Though bioprinting is currently unable to develop mature, implantable tissues, it can pattern cells in 3D constructs with features facilitating maturation and vascularization. Further advances in the field may enable the manufacture of constructs that can mimic native tissues in complexity, spatial heterogeneity, and ultimately, clinical utility. This review studies the use of 3D bioprinting for engineering bone, cartilage, muscle, tendon, ligament, and their interface tissues. Additionally, the current limitations and challenges in the field are discussed and the prospects for future progress are highlighted.

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Section: Introductionmentioning

confidence: 99%

Recent advances in 3D bioprinting of musculoskeletal tissues

et al. 2021

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Revision of Flexor Tendon Repair: Factors Associated With Flexor Tenolysis

Demers

Moran

Bustos

et al. 2022

Hand (New York, N,Y.)

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Background: Tenolysis restores mobility to the flexor tendon through the lysis of adhesions that inhibit and negatively impact functional outcomes following flexor tendon repair. Despite extensive literature on operative techniques and therapy protocols used to minimize adhesion formation, there are limited data examining the association of patient, injury, and postoperative factors with tenolysis. This study aims to: (1) quantify tenolysis rates following flexor tendon repair or reconstruction; and (2) identify patient demographic factors, medical comorbidities, injury characteristics, postoperative diagnoses, and complications associated with tenolysis. Methods: PearlDiver was used to identify patients who underwent a flexor tendon repair or reconstruction from 2010 to 2020. Patients were stratified by whether or not flexor tenolysis was performed. Patient demographics, comorbidities, injury characteristics, postoperative diagnoses, and complications were recorded. Logistic regression analysis was used to identify independent risk factors associated with tenolysis. Results: Database review identified 10 264 patients who underwent either flexor tendon repair or reconstruction, with 612 patients (6.0%) subsequently undergoing tenolysis. Logistic regression analysis determined that vascular injury preceding flexor tendon repair, surgical wound disruption, nerve injury diagnosed postoperatively, postoperative tendon rupture, and need for repeat flexor tendon repair were associated with an increased odds of tenolysis. Patient age, sex, and comorbidities were not associated with performance of tenolysis. Conclusions: Although tenolysis rates may differ according to physician and patient preferences, identification of factors associated with tenolysis following flexor tendon repair allows surgeons to risk-stratify patients prior to surgery and help guide postoperative expectations if complications arise.

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Tendon Injuries

Cited by 2 publications

References 10 publications

Recent advances in 3D bioprinting of musculoskeletal tissues

Recent advances in 3D bioprinting of musculoskeletal tissues

Revision of Flexor Tendon Repair: Factors Associated With Flexor Tenolysis

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