Tendencias de consumo de medicamentos ansiolíticos e hipnóticos en una población colombiana, 2008-2013

Machado‐Alba, Jorge Enrique; Alzate-Carvajal, Verónica; Jiménez-Cañizales, Carlos Eduardo

doi:10.1016/j.rcp.2015.01.007

Cited by 8 publications

(2 citation statements)

References 25 publications

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“…En Colombia se realizó un estudio observacional cuyo objetivo fue determinar el comportamiento del consumo y los costos de los ansiolíticos e hipnóticos en una población de pacientes afiliados al Sistema General de Seguridad Social en Salud. Mostró que el número de pacientes que recibieron un medicamento ansiolítico o hipnótico varió de 11.097 a 19.231 entre 2008 y 2013 (crecimiento de 73,3%), mientras que las prescripciones aumentaron de 14.377 a 33.807 en los seis años del estudio, lo que representa un crecimiento de 135,1% en el consumo de estos medicamentos en Colombia (16) .…”

Section: Introductionunclassified

Descripción de la disponibilidad y normas para el uso de las benzodiazepinas en algunos países de Latinoamérica, 2016

2022

RMU

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El siguiente trabajo no contó con financiación ni otro tipo de apoyo para su elaboración Los autores declaran no tener conflicto de intereses relacionados a su elaboración. Recibido: 20/7/21 Aprobado: 27/4/22 Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) Descripción de la disponibilidad y normas para el uso de las benzodiacepinas en algunos países de América Latina, 2022Description of benzodiazepines availability and regulation in several countries of Latin America, 2022 Descrição da disponibilidade e regulamentação para o uso de benzodiazepínicos em alguns países da América Latina, 2022

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Section: Introductionunclassified

Descripción de la disponibilidad y normas para el uso de las benzodiazepinas en algunos países de Latinoamérica, 2016

2022

RMU

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“…In South American countries, including Colombia, GAD is also treated mainly with benzodiazepines such as diazepam, clonazepam, alprazolam, and lorazepam [ 12 , 13 ]. However, plant-based drugs are popular since patients consider them as a natural, effective, and safe alternative to treat anxiety [ 14 ].…”

Section: Introductionmentioning

confidence: 99%

Pharmacological Evaluation of Mentha spicata L. and Plantago major L., Medicinal Plants Used to Treat Anxiety and Insomnia in Colombian Caribbean Coast

Daneiva

Rivera

Ocampo

et al. 2018

Evidence-Based Complementary and Alternative Medicine

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Anxiety disorders are highly prevalent, chronic, and disabling conditions that impose enormous health and economic costs both on individuals and on society. Medicinal plants are an invaluable source of bioactive metabolites that can be useful as new pharmacological treatment. Teas from Mentha spicata and Plantago major are employed by Colombian populations to treat stress and insomnia. This work was conducted to evaluate their anxiolytic and hypnotic properties. For this, we employed the Elevated Plus-Maze test and the sodium pentobarbital-induced hypnosis method using Wistar rats. Oral administration of M. spicata extract (1000 mg/Kg) significantly increased the exploration and time spent in the open arms, which indicates its anxiolytic activity. On the other hand, both M. spicata and P. major extracts (1000 mg/Kg) remarkably augmented the sleeping time induced by pentobarbital, suggesting a sedative and hypnotic effect of the plants extracts. In addition, the acute toxicological study demonstrated that the doses used did not induce mortality or toxicity effects at hepatic or renal level. The bioactivity seems to be related to several kinds of constituents, mainly phenolic compounds such as flavonoids and tannins. In conclusion, these results reinforce the potential use of these species in the therapy of anxiety.

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Availability of secondary healthcare data for conducting pharmacoepidemiology studies in Colombia: A systematic review

Franco¹,

Vizcaya²

2020

Pharmacology Res & Perspec

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Tendencias de consumo de medicamentos ansiolíticos e hipnóticos en una población colombiana, 2008-2013

Cited by 8 publications

References 25 publications

Descripción de la disponibilidad y normas para el uso de las benzodiazepinas en algunos países de Latinoamérica, 2016

Descripción de la disponibilidad y normas para el uso de las benzodiazepinas en algunos países de Latinoamérica, 2016

Pharmacological Evaluation of Mentha spicata L. and Plantago major L., Medicinal Plants Used to Treat Anxiety and Insomnia in Colombian Caribbean Coast

Availability of secondary healthcare data for conducting pharmacoepidemiology studies in Colombia: A systematic review

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