Tendência da mortalidade por tuberculose no estado do Paraná, Brasil – 1998 a 2012

Cecílio, Hellen Pollyanna Mantelo; Santos, Aliny de Lima; Marcon, Sônia Silva; Latorre, Maria do Rosário Dias de Oliveira; Mathias, Thaís Aidar de Freitas; Rossi, Robson Marcelo

doi:10.1590/1413-81232018231.25242015

Cited by 14 publications

(18 citation statements)

References 12 publications

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“…A study regarding the tendency of TB mortality in Paraná from 1998 to 2012 demonstrated that there was initially a decrease, and an increase tendency in the years 2010 to 2012 (Cecilio et al 2018), which was not confirmed by the present study.…”

Section: Discussioncontrasting

confidence: 99%

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Early death by tuberculosis as the underlying cause in a state of Southern Brazil: Profile, comorbidities and associated vulnerabilities

Oliveira

Silveira

Beraldi-Magalhães

et al. 2019

International Journal of Infectious Diseases

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To know the profile of adults who died by tuberculosis as the main cause, the time interval between the diagnosis and death, associated comorbidities and vulnerabilities. Method: Observational study of secondary data regarding deaths by tuberculosis that occurred in the State of Paraná, Brazil, from 2008 to 2015. A linkage between the databases of mortality and tuberculosis notification system was conducted for data enrichment. Frequency tables, Exact Fisher test and Z test have identified statistical associations. Results: Linkage points out 12.1% (115/944) of under-reporting in the 944 deaths identified. Early deaths accounted for 74.6% (705/944). The male sex (75.8%) was associated with the early death group. Almost half of the deaths reported in notification system (414/829) had one or more vulnerabilities. Early death were associated with respiratory system diseases and symptoms (p = 0.0001) and mental and behavioral disorders (p = 0.0001). Conclusion: High number of early deaths due TB indicate the need to seek out the respiratory symptomatic and use faster diagnostic methods. Strategies for treatment adherence, adequate monitoring of comorbidities and multisectorial support may prevent early and late death. The presence of vulnerabilities indicates that efforts beyond the health sector are needed in order to eliminate tuberculosis as public health problem.

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Section: Discussioncontrasting

confidence: 99%

“…The mortality rate for TB in HIV-negative individuals, on the other hand, was 2.2 and 1.0 in Brazil and Paraná, respectively (Brasil, 2016). Study from 1998 to 2012, also in Paraná, had already indicated an increase in mortality due TB since 2010 (Cecilio et al 2018).…”

Section: Introductionmentioning

confidence: 99%

Early death by tuberculosis as the underlying cause in a state of Southern Brazil: Profile, comorbidities and associated vulnerabilities

Oliveira

Silveira

Beraldi-Magalhães

et al. 2019

International Journal of Infectious Diseases

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“…Combined with individual characteristics, they are also an important risk contributor to TB mortality [22]. The prevalent characteristics of TB mortality in our socio-demographic profile were male sex, mixed-race, age between 40 and 59 years, and low educational attainment-corroborating investigations around the world [9,13,23]. New strategies that improve the quality of life of the population with TB and reduce the number of cases that abandon treatment, as well as the number of recurrences of TB and deaths from TB, are fundamental to morbidity and mortality control [24].…”

Section: Discussionsupporting

confidence: 80%

Determinants associated with areas with higher tuberculosis mortality rates: an ecological study

Lima

Rocha

Araújo

et al. 2019

Tropical Med Int Health

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Objective To characterise tuberculosis deaths in a region of northeast Brazil during the period from 2006 to 2017 and to identify determinants associated with areas with higher tuberculosis mortality rates. Methods Ecological descriptive study of deaths from tuberculosis with multivariate mapping and logistic regression, carried out from 2006 to 2017 in the 75 municipalities of Sergipe, Brazil. The focus of the analysis was the mean mortality rate from tuberculosis, dichotomised according to the median. The independent variables were selected based on the conceptual model of the social determinants of health. Results Mortality due to tuberculosis in Sergipe, Brazil, was most prevalent among males, mixed‐race people, and people over 40 years old and with a low level of education. Multivariate logistic regression identified the mean incidence rate for tuberculosis (aOR: 1.06), the proportion of HIV testing (aOR: 7.10), people without primary education and with informal occupation (aOR: 1.26) and people living in urban households without waste collection service (aOR: 0.10) as determinants associated to municipalities with higher tuberculosis mortality rates, with area under the ROC curve of 84% (P‐value 0.000). Mapping revealed evident spatial variability. Conclusions The tuberculosis epidemic in Brazil is determined by access to health services, especially the provision of HIV testing among those diagnosed with tuberculosis, accelerated urbanisation with large pockets of poverty and unsanitary housing conditions, corroborating global trends.

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“…Ademais, deve-se ressaltar que a testagem HIV/TB tem grande influência, visto que é preconizado que todos os pacientes com diagnóstico de tuberculose realizem a testagem para HIV, o que não acontece na maioria dos atendimentos 26 .…”

Section: Resultsunclassified

“…No tocante ao diagnóstico, a literatura demonstra que, apesar do raio X, baciloscopia e cultura serem métodos diagnósticos importantes quando existe suspeita de TB, menos de 20% das crianças com o diagnóstico apresentam baciloscopia positiva, enquanto que a cultura detecta M. tuberculosis em menos de 50% dos casos [25][26][27] . O presente estudo evidenciou que a maioria dos achados clínicos radiológicos (67,8%) indicaram a suspeita clínica de TB, porém houve parcelas importantes de mudança de diagnóstico, o que sinaliza dificuldades para o correto diagnóstico na população pediátrica.…”

Section: Resultsunclassified

Tuberculose em crianças e adolescentes: uma análise epidemiológica e espacial no estado de Sergipe, Brasil, 2001-2017

Santos

Cruz

Lima

et al. 2020

Ciênc. saúde coletiva

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Resumo A tuberculose continua como uma das doenças mais frequentes no mundo e uma das principais causas de morbimortalidade. Dados da Organização Mundial de Saúde indicam que o Brasil responde por 75% dos casos mundiais envolvendo crianças. O estudo objetiva analisar o padrão epidemiológico e espacial da tuberculose em crianças e adolescentes no estado de Sergipe durante o período de 2001 a 2017. Trata-se de um estudo ecológico, de serie temporal, com uso de dados secundários. As variáveis categóricas foram sumarizadas em frequência simples e absoluta. Na análise espacial foi utilizado o método bayesiano para suavização de taxas e o índice de Moran para avaliar a autocorrelação espacial. A análise de tendência foi realizada por meio do modelo de regressão Joinpoint. Verificou que a taxa média de incidência foi de 5,9 com predomínio na faixa etária 15 a 19 anos (76,4%) e tendência estacionaria, porém com variação anual positiva em ambos os sexos. A tuberculose em crianças e adolescentes apresenta dependência espacial significante nas regiões norte e nordeste. O conhecimento da situação epidemiológica da tuberculose ao longo dos anos fornece subsídios para o direcionamento de recursos em áreas de risco e às novas estratégias de prevenção e controle da doença em crianças e adolescentes.

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Tendência da mortalidade por tuberculose no estado do Paraná, Brasil – 1998 a 2012

Cited by 14 publications

References 12 publications

Early death by tuberculosis as the underlying cause in a state of Southern Brazil: Profile, comorbidities and associated vulnerabilities

Early death by tuberculosis as the underlying cause in a state of Southern Brazil: Profile, comorbidities and associated vulnerabilities

Determinants associated with areas with higher tuberculosis mortality rates: an ecological study

Tuberculose em crianças e adolescentes: uma análise epidemiológica e espacial no estado de Sergipe, Brasil, 2001-2017

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