Ten Years’ Survey of Dialysis-Associated Tuberculosis

Abstract

Tuberculosis associated with dialysis was studied at the Renal Unit of the Tokyo Medical and Dental University and Yokosuka Mutual Aid Hospital Kidney Center, in both of which the treatments of chronic renal failure are the same. There were 12 tuberculosis patients out of 367 patients on maintenance hemodialysis from January 1967 to December 1976, an incidence of 3.3%. This was 6–16 times greater than that in the general population of this country according to yearly statistics. The characteristics of dialysis-associated tuberculosis include a high incidence of miliary tuberculosis, especially in aged patients and difficulty in establishing the diagnosis before death. Clinical features which are helpful in the early diagnosis are intermittent high fever of unknown origin, weight loss, anorexia, abnormalities of the central nervous system, erythrocyte sedimentation rate over 100 mm/h, leukocytosis and high value of the C-reactive protein. With the increasing number of dialysis patients, an increase of dialysis-associated tuberculosis is expected and this will be one of the major problems of dialysis patients in future.

Active Tuberculosis in Patients Undergoing Hemodialysis for End-stage Renal Disease: A 9-year Retrospective Analysis in a Single Center

“…The details of the 10 cases examined by QFT-2G are listed in Table 5 Previous studies reported a high frequency of cases of TB discovered in the first year of dialysis (3,4,13,19 HD (HD >1 year) T a b l e 3 . Ra d i o l o g i c a l Cl a s s i f i c a t i o n o f 1 6 P a t i e n t s wi t h P u l mo n a r y T u b e r c u l o s i s …”

The Prevalence and the Characteristics of Tuberculosis Patients Undergoing Chronic Dialysis Treatment: Experience of a Dialysis Center in Southeast Turkey

“…[4,11] The incidence of TB in the various HD populations of the world (Canada, Poland, and Saudi Arabia) varies from 1.6% to 28%. [12][13][14] Acute infection with Mtb occurred in 7.9% of 224.954 patients in HD centers in the United States in 1995. [15] In Turkey, reported incidences of TB in HD patients have ranged from 6.1% to 23.6%.…”

Tuberculin Skin Test and Anergy in Dialysis Patients of a Tuberculosis-Endemic Area

“…Patients on chronic dialysis therapy are at an increased risk of being affected by tuberculosis (TB) [1, 2, 3, 4, 5], most likely because of the impaired cell-mediated immunity associated with end-stage renal disease [6, 7]. Periodical tuberculin skin tests or purified protein derivative (PPD) tests were suggested to detect infected TB patients [8].…”