Ten Years» Experience of Aortic Aneurysm Associated with Systemic Lupus Erythematosus

Abstract

prolonged steroid therapy may play a major role in accelerating atherosclerosis, which can result in aortic aneurysmal enlargement, possibly together with primary aortic wall involvement and/or vasculitic damage in patients with SLE.

Ruptured thoracic aortic aneurysm in patient with systemic lupus erythematosus

“…According to Khan and Spiera [1], nine cases of patients with aortic aneurysm and SLE have been reported. The experience of Ohara et al [4] from 429 patients operated on for abdominal aortic aneurysm shows that only five were associated with SLE.…”

Endovascular Aneurysm Repair (EVAR) of an Infra-Renal Abdominal Aortic Aneurysm (AAA) in a Young Patient with Systemic Lupus Erythematosus (SLE)

“…The pathogenesis has been attributed to circulatory disturbances resulting from vasculitis and cystic medial degeneration as well as atherosclerosis. The occurrence of atherosclerosis is often considered to be due to long-term steroid treatment, hyperlipidemia, hypertension, and nephrotic syndrome [1] described his institution's experience with only 5 SLE patients in over 10 years of treating 429 patients with all aortic aneurysms. 2 Similar to her, 4 of the 5 patients had received long-term corticosteroid treatment with a mean of 23 years.…”

Cardiovascular Involvement in Systemic Lupus Erythematosus

“…(Wilson et al, 1992) Aortic aneurysms can also occur in SLE. (Ohara et al, 2000) 7.2 Diagnosis It is often difficult to distinguish coronary arteritis from accelerated atherosclerosis. Serial coronary angiography has been proposed as the most useful diagnostic modality.…”