Ten‐year pattern of red blood cell use in the North of England

Abstract

Further decreases in surgical RBC use may be achievable but the aging population is likely to demand more blood for nonsurgical indications and efforts should be directed to optimizing use in these recipients. Comparative data on transfusion rates between regions or countries may be a useful tool for improving blood use.

Validation of multisource electronic health record data: an application to blood transfusion data

“…Validation outcomes reported by previous transfusion data warehouse studies are sparse and vary greatly. Most often reported was the linkage rate of transfusions to donors, varying between 92%–99% [20, 22–25] and, vice versa, estimates of wastage of blood products (i.e., issued but not transfused) of 1.3% and 7.7% [22, 23]. The percentage missing values was also reported by some studies: clinical variables were missing for 13% (post-transfusion Hb), 14% (ASA code) [26], and 20% (specialty), with the degree of missingness varying between specialties from 2% to 47% [21] (a more extensive overview per transfusion database is provided in Additional file 1: Table S3).…”

Red Blood Cell Transfusions in Greece: Results of a Survey of Red Blood Cell Use in 2013

“…Adequate transfusion practice is essential in order to cover transfusion demands. Assessing data regarding RBC units transfused at medical institutions nationally could provide the data needed for developing plans to manage the demand and supply for blood units [2,3,4]. The aim of our study was to assess and evaluate the use of RBC units in Greece in order to identify parameters that contribute to proper RBC management, which can ensure blood sufficiency, taking into account the geographical particularities of our country, the large number of transfusion-dependent thalassemia patients, and the large number of car accident victims.…”

Ten‐year patterns in blood product utilization during cardiothoracic surgery with cardiopulmonary bypass in a tertiary hospital

“…Perioperative hemorrhage requiring allogeneic blood product transfusion is ubiquitous in cardiothoracic surgery, leading to an estimated consumption of 10% to 15% of the overall supply of donor blood . In the past decade, the increased awareness of blood conservation techniques substantially reduced perioperative allogeneic blood transfusion .…”

“…Furthermore, limited intraoperative fluid resuscitation, the use of antifibrinolytics, point‐of‐care diagnosis of coagulopathy, and blood conservation by cell salvage may all contribute to limited and transfusion requirements. In contrast, the aging surgical population with additional comorbidities undergoing more complex cardiac surgery, as well as withdrawal of aprotinin by the manufacturer, may have resulted in an augmentation of blood product consumption over the past decade …”

“…The analysis of blood loss and consumption patterns can be of help in understanding key factors for improvement of perioperative blood management, especially since allogeneic blood transfusion has frequently been related to increased mortality . The limited number of studies that evaluate allogeneic blood transfusion patterns, however, mostly discuss a mixture of medical conditions and a broad range of surgical procedures . Particular changes in blood product use during cardiothoracic procedures using CPB over a 10‐year time period in a tertiary hospital are described, specifically focusing on the association of blood conservation strategies with red blood cells (RBCs), fresh‐frozen plasma (FFP), and PLT concentrate transfusion in the context of population and surgical characteristics during nonaortic cardiac surgery.…”