Ten-Year Cumulative Incidence of COPD and Risk Factors for Incident Disease in a Symptomatic Cohort

Lindberg, Anne; Jonsson, Ann-Christin; Rönmark, Eva; Lundgren, R; Larsson, Lars‐Gunnar; Lundbäck, Bo

doi:10.1378/chest.127.5.1544

Cited by 140 publications

(128 citation statements)

References 28 publications

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“…It is possible these symptom-reporting trends may not be generalisable to more severe COPD, but if primary care physicians are engaged in case finding on the basis of symptoms, these reporting differences between males and females may be important in the early detection of COPD and the likelihood of subsequent performance of spirometry for confirmation. Some studies have not shown that phlegm is an under-reported symptom, but do confirm a high symptom prevalence for females with COPD [15], which is consistent with the observation from the EUROSCOP that females had greater prevalence at baseline of all symptoms apart from the presence of phlegm. However, over the 3 yrs of the EUROSCOP, symptom prevalence was similar by gender, a distinctly different outcome to several other studies suggesting that women are more likely than men to report symptoms of COPD, particularly breathlessness, for a given degree of airway obstruction.…”

supporting

confidence: 68%

Mars and Venus in the GP's office

Jenkins¹

2006

European Respiratory Journal

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supporting

confidence: 68%

Mars and Venus in the GP's office

Jenkins¹

2006

European Respiratory Journal

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“…The JEM indicate the presence, intensity, frequency, and/or probability of exposure to a specific agent in a specific job. Lindberg et al (53) found a borderline association to manual work and low educational level and COPD. In 2 studies (39, 52) no statistically significant association between exposure to VGDF and COPD was observed, but both these articles were based on the European Community Respiratory Health Survey (ECRHS) cohort where the age of recruitment was 20-45 years, with a relatively short follow-up time and the outcome was mild COPD equivalent to GOLD stage I.…”

Section: Population-based Studiesmentioning

confidence: 96%

Occupational chronic obstructive pulmonary disease: a systematic literature review

Omland

Würtz

Aasen³

et al. 2013

Scand J Work Environ Health

117

100

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Occupational chronic obstructive pulmonary disease: a systematic literature review by Omland Ø, Würtz ET, Aasen TB, Blanc P, Brisman J, Miller MR, Pedersen OF, Schlünssen V, Sigsgaard T, Ulrik CS, Viskum S This review on occupational chronic obstructive pulmonary disease (COPD) addresses some of the potential limitations of earlier assessments by restricting the studies included to high quality epidemiological analysis involving only spirometrically confirmed air-flow obstruction as the outcome. The authors combined this with minimal requirements for exposure characterization allowing for analysis of population-based studies. Affiliation 19Review Scand J Work Environ Health. 2014;40(1):19-35. doi:10.5271/sjweh.3400 Occupational chronic obstructive pulmonary disease: a systematic literature review Objective Occupational-attributable chronic obstructive pulmonary disease (COPD) presents a substantial health challenge. Focusing on spirometric criteria for airflow obstruction, this review of occupational COPD includes both population-wide and industry-specific exposures.Methods We used PubMed and Embase to identify relevant original epidemiological peer-reviewed articles, supplemented with citations identified from references in key review articles. This yielded 4528 citations. Articles were excluded for lack of lung function measurement, insufficient occupational exposure classification, lack of either external or internal referents, non-accounting of age or smoking effect, or major analytic inadequacies preventing interpretation of findings. A structured data extraction sheet was used for the remaining 147 articles. Final inclusion was based on a positive qualitative Scottish Intercollegiate Guidelines Network (SIGN) score (≥2+) for study quality, yielding 25 population-wide and 34 industry/occupation-specific studies, 15 on inorganic and 19 on organic dust exposure, respectively. ResultsThere was a consistent and predominantly significant association between occupational exposures and COPD in 22 of 25 population-based studies, 12 of 15 studies with an inorganic/mineral dust exposure, and 17 of 19 studies on organic exposure, even though the studies varied in design, populations, and the use of measures of exposure and outcome. A nearly uniform pattern of a dose-response relationship between various exposures and COPD was found, adding to the evidence that occupational exposures from vapors, gas, dust, and fumes are risk factors for COPD. ConclusionThere is strong and consistent evidence to support a causal association between multiple categories of occupational exposure and COPD, both within and across industry groups.Key terms: airflow obstruction; COPD; dust; fume; gas; lung function measurement; occupational exposure; vapor. Chronic obstructive pulmonary disease (COPD) represents serious morbidity and has emerged as a leading cause of death worldwide (1). Although tobacco smoking is the leading factor in the etiology of COPD, the disease may be caused by inhalation of different gases and aerosols among bot...

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“…These studies were also among the earliest publications of incidence of COPD. It was shown that, from the age of 40 yrs, the incidence of COPD in smokers is 1-2 out of 100 per year, while it was 1-2 out of 1,000 per year among nonsmokers [13,14]. It was also demonstrated that start of smoking (before the age of 20 yrs) considerably increases the risk of developing COPD; the risk of 1 yr earlier starting of smoking exceeds smoking of 1 pack?yr -1 as an adult [15].…”

Section: Relationship To the Population: Epidemiological Studiesmentioning

confidence: 99%

Research at the Unit of Lung and Allergy research at Karolinksa Intitutet, Stockholm, Sweden

Larsson

2008

European Respiratory Review

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Ten-Year Cumulative Incidence of COPD and Risk Factors for Incident Disease in a Symptomatic Cohort

Cited by 140 publications

References 28 publications

Mars and Venus in the GP's office

Mars and Venus in the GP's office

Occupational chronic obstructive pulmonary disease: a systematic literature review

Research at the Unit of Lung and Allergy research at Karolinksa Intitutet, Stockholm, Sweden

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