Modern small diameter metal-on-metal (MoM) bearings for total hip arthroplasty (THA) have been developed in the nineteen-eighties to address the problem of polyethylene wear related osteolysis. Subsequently large diameter MoM hip resurfacings (HRA) were designed for young and active patients to preserve bone and avoid dislocation. Large diameter MoM THA were originally meant as an easy femoral component-only revision solution for femoral neck fractures in HRA, but were then advocated for primary THA as well. In the last decade however, increasing numbers of revisions for adverse local tissues reactions (ALTR) to metal debris have been reported. These ALTR are due to excessive wear of the MoM bearings, usually related to malpositioning of the components leading to edge loading, or in rare cases to metal sensitivity. Besides the immunological reactions, metal particles and ions have a potential local and systemic toxicity. Wear and tribocorrosion at the taper-trunnion connections of MoM THA but also THA with polyethylene and ceramic bearings have also been recognized as a cause of ALTR with extensive tissue destruction. Despite the fact that the long-term survivorship and functional results of certain MoM HRA are excellent and better than THA in the young and active patients group, MoM bearings have become very unpopular and are likely to be replaced by bearing couples of other materials. . When an increasing number of these MoP total hip arthroplasties (THA) had to be revised because of progressive loosening and extensive osteolysis caused by a macrophage response to polyethylene (PE) wear particles [6] whilst hip simulator studies were demonstrating substantially less volumetric wear from MoM bearing surfaces [7,8], MoM hip articulations were reintroduced to solve the problem of polyethylene (PE) particle-induced osteolysis. The imperfections regarding geometry, tolerance and metallurgy (low-carbon content associated with higher wear) of the first generation MoM articulations were resolved in the second generation high carbon content Metasul ® MoM bearings (Sulzer/Centerpulse, Winterthur, Switzerland, 1988), which exhibited very promising short-and medium term results [9]. Furthermore, in the nineties, modern MoM hip resurfacing arthroplasty (HRA) (Figure 1) was proposed to address the inferior clinical results of THA in young and active
Keywords