Temporomandibular Joint Biomechanical Restrictions

Cascone, Piero; Vetrano, Stefano; Nicolai, G; Fabiani, Francesco

doi:10.1097/00001665-199907000-00003

Cited by 7 publications

(4 citation statements)

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“…Although it commonly involves the knee, 5 it may occur in the TMJ. The disease is characterized by the development of cartilaginous nodules within the synovial space from the synovial connective tissue matrix; 21 the nodules subsequently degraded, detached, and become fluctuating intrarticular bodies tending to calcify in the joint space. The involved joint space may also become widened with possible articular erosions, eventually leading to secondary osteoarthritis.…”

Section: Discussionmentioning

confidence: 99%

Innovative Surgical Management of the Synovial Chondromatosis of Temporo-Mandibular Joints

Ionna

Amantea

Mastrangelo

et al. 2016

Journal of Craniofacial Surgery

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Synovial chondromatosis (SC) is an uncommon disease characterized by a benign nodular cartilaginous proliferation arising from the joint synovium, bursae, or tendon sheaths. Although the temporomandibular joint is rarely affected by neoplastic lesions, SC is the most common neoplastic lesion of this joint. The treatment of this disease consists in the extraoral surgery with a wide removal of the lesion; in this study, the authors described a more conservative intraoral surgical approach. Patient with SC of temporomandibular joint typically refer a limitation in the mouth opening, together with a persistent not physiological mandibular protrusion and an appearance of a neoformation located at the right preauricular region: the authors reported 1 scholar patient. After biopsy of the neoformation, confirming the synovial chondromatosis, the patient underwent thus to the surgical excision of the tumor, via authors' conservative transoral approach, to facilitate the enucleation of the neoformation. The mass fully involved the pterygo-maxillary fossa with involvement of the parotid lodge and of the right TMJ: this multifocal extension suggested for a trans-oral surgical procedure, in the light of the suspicion of a possible malignant nature of the neoplasm. Our intraoral conservative approach to surgery is aimed to reduce the presence of unaesthetic scars in preauricular and facial regions, with surgical results undoubtedly comparable to the traditional surgical techniques much more aggressive. Our technique could be a valid, alternative, and safe approach to treat this rare and complex kind of oncological disease.

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Section: Discussionmentioning

confidence: 99%

Innovative Surgical Management of the Synovial Chondromatosis of Temporo-Mandibular Joints

Ionna

Amantea

Mastrangelo

et al. 2016

Journal of Craniofacial Surgery

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“…The synovial membrane cells were disposed in rows, facing the articular cavity (Nozawa‐Inoue et al,2003; Tong and Tideman,2001) and it was composed by a synovial layer supported by a loose connective tissue layer densely vascularized and innervated, called subsynovial layer (Cascone et al,1999; Piette,1993). According to the present data, it was observed a synovial layer with cells aligned in one to three rows interposed by bundles of collagen fibers and there was a reduction in the number of these cells with ageing.…”

Section: Discussionmentioning

confidence: 99%

Biophysical characterization of polymyxin b interaction with LPS aggregates and membrane model systems

Domingues¹,

Inácio²,

Raimundo³

et al. 2012

Biopolymers

130

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Antibiotic resistance is an increasingly severe health problem. Antimicrobial peptides (AMPs) are being developed in order to overcome this problem, due lower bacterial resistance. Polymyxin B is an AMP with bactericidal effect on Gram-negative bacteria due to its high affinity for lipopolysaccharide (LPS). The objective of this work was to unravel the polymyxin B mechanisms of LPS neutralization and bactericidal activity. Using dynamic light scattering, it was observed that polymyxin B induces LPS aggregation in a concentration-dependent manner. The peptide increases the surface charge of LPS and membrane model systems, as revealed by zeta-potential measurements. The higher zeta-potential variations were detected in the presence of the negatively charged POPG membranes. This higher interaction with negatively charged membranes, made of POPG, was followed at higher peptide concentration by membrane permeabilization. Also, for zwitterionic POPC membranes a higher membrane leakage was detected. The peptide promotion of LPS aggregation may be related with the clearance of LPS from the bloodstream, eventually by facilitating macrophage phagocytosis and/ or blocking the binding of LPS to its receptor. Our data indicate that polymyxin B mechanism of action at the molecular level involves a first step of electrostatic approach toward LPS; then, it may be internalized and bind to the bacterial phosphatidylglycerol-rich membrane leaflets, inducing leakage at higher peptide concentrations.

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“…The real challenge was the differential diagnosis between TMJ locking typical of internal derangement (ID) and MO. 22,23 At first, he was treated as a patient affected by ID, but after an inner period of wellness secondary to TMJ surgery, the patient referred a major limitation of mouth opening without pain.…”

Section: Discussionmentioning

confidence: 99%

Myositis Ossificans of the Medial Pterygoid Muscle

Ramieri

Bianca

Arangio

et al. 2010

Journal of Craniofacial Surgery

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Myositis ossificans (MO) is a disease whose main feature is the formation of heterotopic bone involving muscle or any other soft tissue. Pathogenesis is not all clear, but trauma is universally recognized as a trigger event. Myositis ossificans can be divided into 2 classifications: MO progressiva and MO traumatica. The authors present a case of a 64-year-old man who was diagnosed with MOT of the left medial pterygoid muscle. The patient had a long clinical history of signs and symptoms of temporomandibular articulation related to previous conditions, and no major traumatic events were reported, apparently related to MOT.

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Temporomandibular Joint Biomechanical Restrictions

Cited by 7 publications

References 0 publications

Innovative Surgical Management of the Synovial Chondromatosis of Temporo-Mandibular Joints

Innovative Surgical Management of the Synovial Chondromatosis of Temporo-Mandibular Joints

Biophysical characterization of polymyxin b interaction with LPS aggregates and membrane model systems

Myositis Ossificans of the Medial Pterygoid Muscle

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