Temporal Triangular Alopecia in Association With Mental Retardation and Epilepsy in a Mother and Daughter

Successful Treatment of Temporal Triangular Alopecia by Hair Restoration Surgery Using Follicular Unit Transplantation

“…21 Simultaneous occurrence of TTA with aplasia cutis congenital, 16 mental retardation and epilepsy, 3 and Down syndrome 22 has also been described.…”

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“…Exclamation mark hairs are absent and hair pull test is negative [5]. Histopathologically, hair follicles are markedly miniaturized or absent [6,8,9]. We were unable to histopathological examination of the lesions because the parents did not allow for biopsy.…”

“…This entity usually occurs as an isolated anomaly but it may also be a part of a multisystemic birth anomalies such as serebellar-trigeminal-dermal dysplasia (Gomez-LopezHernandez (GLH) syndrome) or phacomatosis pigmentovascularis type-2 [4,6]. In the other hand the condition may occur as part of a syndrome with autosomal-dominant inheritance [9]. Rarely, the lesion may involve large temporoparietal area which can be a characteristic component of GLH syndrome (craniosynostosis, midfacial hypoplasia, trigeminal anesthesia, cerebellar dysplasia and mental deficiency) [5].…”

A Very Rare Cause of Localized Nonscarring Alopecia: Nevus Psiloliparus- a case Review

“…In isolated cases of NP, except for the other acquired or congenital reasons for circumscribed hair loss such as alopecia areata (AA), aplasia cutis congenita (ACC) or temporal triangular alopecia (TTA), due to the lipodematous appearance and soft consistency of the masses, especially solitary lipomas of the scalp [1], lipodematous scalp (LS) and lipodematous alopecia (LA) should be considered in differential diagnoses. In AA, which is an autoimmune and acquired condition, presence of exclamation mark hairs and positive hair pull test are important distinguishing findings [14][15][16]. ACC is another rare scalp anomaly which is usually characterized by a localized, complete or partial absence of skin at birth.…”

“…I is characterized by usually sporadic but rarely syndromal, earlyonset, unilateral and well-circumscribed, triangular or lancet-shaped, non-cicatricial hypotrichosis in the frontotemporal area, and usually manifests after 2 years of age. The lesion is distinguished from AA with the typical history, shape and location of the lesion, absence of exclamation mark hairs, negative hair pull test, typical miniaturized vellus hairs with normal density [14][15][16], and, it can also be distinguished from NP with absence of increased fatty tissue and orphaned hyperplasia of erector pili muscles [1][2][3]5]. On the other hand, the last two conditions mentioned above (LS and LA) have been considered as distinct entities by some authors, while some others have evaluate that the LA was an advanced form of LS.…”