Temporal trends of organochlorines in Northern Europe, 1967–1995. Relation to global fractionation, leakage from sediments and international measures

Bignert, Anders; Olsson, Mats; Persson, Wawa; Jensen, Søren Krogh; Zakrisson, Susanne; Litzén, Kerstin; Eriksson, Urban; Häggberg, Lisbeth; Alsberg, Tomas

doi:10.1016/s0269-7491(97)00191-7

Cited by 287 publications

(182 citation statements)

References 32 publications

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“…2,2-Bis(4-chlorophenyl)-1,1,1-trichloroethane (4,4´-DDE) and persistent PCB congeners are in general and still the most abundant pollutants in wildlife and humans, although recent decreases have been reported (2,3). High concentrations of these substances have been determined even in populations living in remote areas (4,5), including people from the Faroe Islands, as first documented by analyses of four pools of human breast milk sampled from a birth cohort in 1987 (6).…”

mentioning

confidence: 99%

Hydroxylated PCB Metabolites and PCBs in Serum from Pregnant Faroese Women

Fängström¹,

Athanasiadou²,

Grandjean³

et al. 2002

Environ Health Perspect

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mentioning

confidence: 99%

Hydroxylated PCB Metabolites and PCBs in Serum from Pregnant Faroese Women

Fängström¹,

Athanasiadou²,

Grandjean³

et al. 2002

Environ Health Perspect

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“…Since the end of the 1960's, when the Baltic Sea environment was found to be severely polluted by DDT and PCB, continuous temporal monitoring of contaminants has been conducted in Sweden (Bignert et al 1998). Levels of DDT have been decreasing since the program started in 1968, as have levels of PCBs since 1976.…”

Section: Discussionmentioning

confidence: 99%

“…Although current concentrations of POPs found in the Bothnian Bay (the most northern part of the Baltic Sea) are similar to those found off the Swedish west coast (Bignert et al 1998), the Swedish National Food Administration still recommend restricted consumption of fatty fish from the Baltic Sea (http://www.slv.se).…”

Section: Introductionmentioning

confidence: 92%

“…The consumption of locally caught fish among fishermen's families from the west coast of Sweden is comparable to that of the fishermen's families on the Swedish east coast (Rylander et al 1995). However, since the fish caught off the west coast is contaminated (Bergqvist et al 1989, Bignert et al 1998, the fishermen's families on the west coast were not as exposed as their counterparts on the east coast. Indeed, higher mean concentrations of the POP biomarker 2,2'4,4',5,5'-hexachlorobiphenyl (CB-153) and p,p'-DDE has been found among east coast fishermen (297 ng/g lipid CB-153 and 433 ng/g lipid p,p'-DDE) than among west coast fishermen (190 ng/g lipid CB-153 and 241 ng/g lipid p,p'-DDE; Anna Rignell-Hydbom, personal communication).…”

Section: Introductionmentioning

confidence: 94%

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Menarche in women with high exposure to persistent organochlorine pollutants in utero and during childhood

Axmon

2006

Environmental Research

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In animal studies, exposure to persistent organochlorine pollutants (POPs) in utero and through mother's milk has been suggested to affect the onset of puberty. However, human studies are scarce and ambiguous. In the present study, information on age at menarche was collected from 545 women who had been brought up in a fishing village/family at the Swedish east coast, off the Baltic Sea, and therefore were assumed to have been exposed to POPs in utero, through breast feeding, and/or through dietary habits during their childhood. The average age at menarche for these women was compared to that of three referent groups: a) 1252 women who also had been brought up in a fishing village/family, but at the Swedish west coast where the fish had been considerably less contaminated, b) 634 women from the east coast, but who had not grown up in a fishing village/family, and c) 869 women from the west coast who had not grown up in a fishing village/family. Based on previous studies, all groups were regarded has having similar socio-economic circumstances. Data were analyzed using analysis of variance (ANOVA). In an attempt to account for variations in environmental concentrations of POPs over time, all analyses were adjusted for year of birth. Exposed women were found to be slightly older at menarche than referent women from the same coastal area (mean age 13.0 years vs. 12.8 years). No differences were found between the exposed women and the two other referent groups (mean age 13.0 years in all groups).

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“…This was the period when there were PCB-induced effects reported such as reproductive impairment fisheating Baltic seals. The mean level was as 2.5 mg/kg lipid (Bignert et al, 1998), which corresponds to 7.5 µg PCB153/kg ww, and defines the threshold between status class III and IV in the assessment criteria. Application factors of 10 and 100 are then used to set the remaining borders between status classes (Table 3.6).…”

Section: Assessment Criteria For Pcb153 In Fishmentioning

confidence: 99%