Temporal trends of hepatitis C virus transmission in internally displaced people who inject drugs in Odessa, Ukraine

Yakovleva, Anna; Kovalenko, Ganna; Redlinger, Matthew; Smyrnov, Pavlo; Tymets, Olga; Korobchuk, Ania; Kotlyk, Lyudmyla; Kolodyazeva, Ganna; Podolina, Ganna; Chernyavskaya, S. A.; Strathdee, Steffanie A.; Friedman, Samuel R.; Goodfellow, Ian; Wertheim, Joel O.; Bortz, Eric; Meredith, Luke W.; Vasylyeva, Tetyana I.

doi:10.1101/2021.12.28.21268494

Cited by 3 publications

(2 citation statements)

References 34 publications

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“…42 Additionally, for blood transmittable pathogens such as hepatitis C, accounting for the high use of injecting drugs, prevention measures need to be implemented early; surges in hepatitis C transmission were observed in internally displaced Ukrainians. 56 This finding emphasises the need for screening for communicable diseases in Ukrainian refugees using a universal risk-based approach. 57 Next, given the contribution of key populations to the Ukraine HIV epidemic, systems to support people at risk for suboptimal drug exposure, or in whom the consequences of suboptimal therapy are high, are necessary.…”

Section: Urgent Phasementioning

confidence: 91%

Unified European support framework to sustain the HIV cascade of care for people living with HIV including in displaced populations of war-struck Ukraine

et al. 2022

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Section: Urgent Phasementioning

confidence: 91%

Unified European support framework to sustain the HIV cascade of care for people living with HIV including in displaced populations of war-struck Ukraine

et al. 2022

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“…Rapid, portable and relatively cheap genetic sequencing technologies (i.e. MinION from Nanopore) have also shown promise in viral infections monitoring in resource-limited settings [84] and could be used in field settings to generate insights into the dynamics of chronic viral infections transmission in forced migrants [85], although their application for HIV is still in development.…”

Section: Harnessing Momentum To Achieve Hiv Equitymentioning

confidence: 99%

Left behind on the path to 90‐90‐90: understanding and responding to HIV among displaced people

et al. 2022

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Introduction:In 2021, the number of people affected by displacement worldwide reached the highest on record, with an estimated 30.5 million refugees and 4.6 million asylum seekers seeking safety across international borders and further 53.2 million people displaced within their countries of origin. Most forcibly displaced persons come from or relocate to lower-and middle-income countries (LMICs) and many of those countries have large HIV epidemics. In this commentary, we describe some of the challenges at the intersection of HIV and displacement vulnerabilities that cannot be easily addressed in resourcelimited environments. Discussion: HIV transmission and prevention and treatment efforts in the context of displacement are affected by myriad behavioural, social and structural factors across different stages of the displacement journey. For example, structural barriers faced by people experiencing displacement in relation to HIV prevention and care include funding constraints and legal framework deficiencies. Such barriers prevent all forced migrants, and particularly those whose sexual identities or practices are stigmatized against, access to prevention and care equal to local residents. Xenophobia, racism and other social factors, as well as individual risky behaviours facilitated by experiences of forced migration, also affect the progress towards 90-90-90 targets in displaced populations. Current evidence suggests increased HIV vulnerability in the period before displacement due to the effect of displacement drivers on medical supplies and infrastructure. During and after displacement, substantial barriers to HIV testing exist, though following resettlement in stable displacement context, HIV incidence and viral suppression are reported to be similar to those of local populations. Conclusions: Experiences of often-marginalized displaced populations are diverse and depend on the context of displacement, countries of origin and resettlement, and the nature of the crises that forced these populations to move. To address current gaps in responses to HIV in displacement contexts, research in LMIC, particularly in less stable resettlement settings, needs to be scaled up. Furthermore, displaced populations need to be specifically addressed in national AIDS strategies and HIV surveillance systems. Finally, innovative technologies, such as point-of-care viral load and CD4 testing, need to be developed and introduced in settings facing displacement.

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Will the Russian war in Ukraine unleash larger epidemics of HIV, TB and associated conditions and diseases in Ukraine?

Friedman,

Smyrnov,

Vasylyeva

2023

Harm Reduct J

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The Russian war in Ukraine poses many risks for the spread of HIV, TB and associated conditions, including possible increases in the numbers of people who inject drugs or engage in sex work in the years ahead. Ukrainian civil society and volunteer efforts have been able to maintain and at times expand services for HIV Key Populations. The extent of mutual-aid and volunteer efforts as well as the continued strength and vitality of harm reduction organizations such as the Alliance for Public Health and the rest of civil society will be crucial resources for postwar efforts to assist Key Populations and prevent the spread of HIV, TB and other diseases. The postwar period will pose great economic and political difficulties for Ukrainians, including large populations of people physically and/or psychically damaged and in pain who might become people who inject drugs. Local and international support for public health and for harm reduction will be needed to prevent potentially large-scale increases in infectious disease and related mortality.

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Temporal trends of hepatitis C virus transmission in internally displaced people who inject drugs in Odessa, Ukraine

Cited by 3 publications

References 34 publications

Unified European support framework to sustain the HIV cascade of care for people living with HIV including in displaced populations of war-struck Ukraine

Unified European support framework to sustain the HIV cascade of care for people living with HIV including in displaced populations of war-struck Ukraine

Left behind on the path to 90‐90‐90: understanding and responding to HIV among displaced people

Will the Russian war in Ukraine unleash larger epidemics of HIV, TB and associated conditions and diseases in Ukraine?

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