Temporal Trends in the Incidence and Natural History of Diverticulitis: A Population-Based Study

Bharucha, Adil E.; Parthasarathy, Gopanandan; Ditah, Ivo; Fletcher, Joel G.; Ewelukwa, Ofor; Pendlimari, Rajesh; Yawn, Barbara P.; Melton, L. Joseph; Schleck, Cathy D.; Zinsmeister, Alan R.

doi:10.1038/ajg.2015.302

Cited by 234 publications

(230 citation statements)

References 47 publications

(56 reference statements)

Supporting

Mentioning

206

Contrasting

Unclassified

Order By: Relevance

“…First, consistent with previous studies [8,20] showing a rise in the incidence of diverticulitis, we found the rate of ED visits with a primary diagnosis of diverticulitis per 100,000 ED visits increased by 19.3% between 2006 and 2013. Second, the aggregate national cost (in 2015 dollars) of diverticulitis ED visits in 2013 was over $1.6 billion representing a 105% increase in cost from 2006.…”

Section: Discussionsupporting

confidence: 92%

“…[2–4] Diverticulitis is the most common complication of diverticular disease with previous estimates varying between 10–25% of individuals with diverticulosis [5,6], however, recent estimates suggest that the rate may be significantly lower [7]. Among individuals in Olmstead County, the incidence of diverticulitis increased by 50% between 1990–1999 and 2000–2007, with a particularly notable rise in younger individuals [8]. The development of acute diverticulitis is associated with obesity, smoking, diet, lack of physical activity, and the use of nonsteroidal anti-inflammatory drugs [9].…”

Section: Introductionmentioning

confidence: 99%

“…The development of acute diverticulitis is associated with obesity, smoking, diet, lack of physical activity, and the use of nonsteroidal anti-inflammatory drugs [9]. Younger individuals with diverticulitis tend to have similar or less severe disease, though they tend to be re-admitted more frequently [8,10,11]. …”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Emergency Department Burden of Diverticulitis in the USA, 2006–2013

et al. 2017

View full text Add to dashboard Cite

Goals The aim of this study was to analyze recent trends in ED visits for diverticulitis between 2006 and 2013. Background Acute diverticulitis is a serious medical condition that frequently leads to emergency department (ED) visits, hospitalizations, and surgeries resulting in a significant health care burden. Methods Data were obtained from the National Emergency Department Sample (NEDS) records in which diverticulitis (ICD-9-CM codes 562.11 and 562.13) was the primary diagnosis in the ED between 2006 and 2013. The NEDS collects data from more than 25 million visits in over 950 hospital emergency departments and is weighted to provide national estimates. Our findings reflected patient and hospital characteristics such as demographics, geographical region, and total charges for ED and inpatient stays. Results Between 2006 and 2013, the rate of diverticulitis-related ED visits increased by 26.8% from 89.8 to 113.9 visits per 100,000 population. The aggregate national cost of diverticulitis-related ED visits increased by 105%, from approximately $822 million in 2006 to over $1.6 billion in 2013. Cost data were adjusted for inflation and reported in 2015 dollars. The percentage of individuals admitted to the same hospital from the ED decreased from 58.0% to 47.1% from 2006 to 2013 respectively while the rate of bowel surgeries per 100,000 ED visits for diverticulitis decreased 33.7% from 2006 to 2013. Conclusions The number of ED visits due to diverticulitis and associated costs continued to rise between 2006 and 2013, while the rate of bowel surgeries and inpatient admissions through the ED for diverticulitis decreased.

show abstract

Section: Discussionsupporting

confidence: 92%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Emergency Department Burden of Diverticulitis in the USA, 2006–2013

et al. 2017

View full text Add to dashboard Cite

show abstract

“…In left-sided colonic diverticulitis without abscess or perforation, the recurrence rate was 13% in patients who were diagnosed with colonic diverticulitis based on imaging findings [173] and 47% in patients diagnosed based on symptoms [174]. Furthermore, only 2-5% of patients with recurrent colonic diverticulitis had newly developed abscess or perforation and needed emergency surgery, indicating that the severity of recurrent colonic diverticulitis is relatively mild [175]. In a recent population-based study, the recurrence rate of colonic diverticulitis was 8% at 1 year, 17% at 5 years, and 22% at 10 years.…”

Section: Cq40: What Is the Recurrence Rate Of Colonic Diverticulitismentioning

confidence: 99%

Guidelines for Colonic Diverticular Bleeding and Colonic Diverticulitis: Japan Gastroenterological Association

et al. 2019

View full text Add to dashboard Cite

Colonic diverticular disease has been increasing in prevalence in Japan due to the rapidly aging population. Colonic diverticular bleeding can result in hemorrhagic shock requiring blood transfusion, and it carries a high risk of recurrence within 1 year. Colonic diverticulitis can cause abscess, fistula formation, and perforation of the colon that may require surgery, and it often recurs. As a result, patients with colonic diverticular disease are often bothered by required frequent examinations, re-hospitalization, and a consequent decrease in quality of life. However, the management of diverticular disease differs between Japan and Western countries. For example, computed tomography (CT) is readily accessible at Japanese hospitals, so urgent CT may be selected as the first diagnostic procedure for suspected diverticular disease. Endoscopic clipping or band ligation may be preferred as the first endoscopic procedure for diverticular bleeding. Administration of antibiotics and complete bowel rest may be considered as first-line therapy for colonic diverticulitis. In addition, diverticula occur mainly in the sigmoid colon in Western countries, whereas the right side or bilateral of the colon is more commonly involved in Japan. As such, diverticular disease in the right-side colon is more prevalent in Japan than in Western countries. Against this background, concern is growing about the management of colonic diverticular disease in Japan and there is currently no practice guideline available. To address this situation, the Japanese Gastroenterological Association decided to create a clinical guideline for colonic diverticular bleeding and colonic diverticulitis in collaboration with the Japanese Society of Gastroenterology, Japan Gastroenterological Endoscopy Society, and Japanese Society of Interventional Radiology. The steps taken to establish this guideline involved incorporating the concept of the GRADE system for rating clinical guidelines, developing clinical questions (CQs), accumulating evidence through a literature search and review, and developing the Statement and Explanation sections. This guideline includes 2CQs for colonic diverticulosis, 24 CQs for colonic diverticular bleeding, and 17 CQs for diverticulitis.

show abstract

“…However, in a population-based study that reviewed the records of 3,222 patients with acute diverticulitis with a 10-year follow-up, recurrent diverticulitis occurred after the index and second diverticulitis episodes in 22 and 55% of patients, respectively. Female gender and younger age were associated with higher recurrence rate [4, 7]. …”

Section: Recurrent Diverticulitis: Risk Factorsmentioning

confidence: 99%

Recurrent Acute Diverticulitis: When to Operate?

et al. 2018

View full text Add to dashboard Cite

Objective: Recurrent acute diverticulitis carries a major burden to any form of health care. Patients present repeatedly to medical centers with a multitude of symptoms and may require different modalities of treatment with significant morbidities and impact on quality of life. Methods: We therefore wanted to identify factors that would imply the need and time of surgery versus conservative management. The literature was thoroughly searched for major studies tackling this topic. Furthermore, studies reporting on decision making based on quality of life were included. Risks of developing recurrent diverticulitis and the potential need of surgery were identified. Relevant surgical details that would decrease recurrence were also denoted. Results: Surgery has been the mainstay of treatment for quite some time. However, the paradigms of treatment have changed over the last few years, especially when long-term population studies confirmed that not all patients require surgical treatment with its associated risk of morbidity. Conclusion: Treatment now has to be patient-tailored with special attention to the subgroup of high-risk patients. These patients must be adequately selected, identifying the impact of the disease on the quality of life and weighing in the risks of the surgical intervention.

show abstract

Temporal Trends in the Incidence and Natural History of Diverticulitis: A Population-Based Study

Cited by 234 publications

References 47 publications

Emergency Department Burden of Diverticulitis in the USA, 2006–2013

Emergency Department Burden of Diverticulitis in the USA, 2006–2013

Guidelines for Colonic Diverticular Bleeding and Colonic Diverticulitis: Japan Gastroenterological Association

Recurrent Acute Diverticulitis: When to Operate?

Contact Info

Product

Resources

About