Temporal Trends in the Incidence and Disability Adjusted Life Years of Schizophrenia in China Over 30 Years

Dong, Wanyue; Liu, Yunning; Sun, Jianzhong; Liu, Yan; Sun, Zhonghe; Bai, Ruhai

doi:10.3389/fpsyt.2022.831188

Cited by 13 publications

(8 citation statements)

References 41 publications

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“…We used an APC model to assess the trend of NPC incidence and mortality in China, and to assess the potential age, period, and cohort effects impact on these trends. The APC can be generally expressed as following [10]:…”

Section: Statistical Analysesmentioning

confidence: 99%

Incidence and mortality trends of nasopharynx cancer from 1990 to 2019 in China: an age-period-cohort analysis

Bai

Sun

et al. 2022

BMC Public Health

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Background Nasopharynx cancer (NPC) is a great health burden in China. This study explored the long-term trends of NPC incidence and mortality in China. Methods We retrospectively analyzed data from the Global Burden of Disease Study 2019 using an age-period-cohort framework. Results The age-standardized incidence rate (ASIR) of NPC increased by 72.7% and age-standardized mortality rate (ASMR) of NPC decreased by 51.7% for both sexes between 1990 and 2019. For males, the local drift for incidence was higher than 0 (P < 0.05) in those aged 20 to 79 years. For females, the local drift was higher than 0 (P < 0.05) in those aged 30 to 59 years, and lower than 0 (P < 0.05) in those aged 65 to 84 years. The local drift for mortality rates were less than 0 (P < 0.05) in every age group for both sexes. The estimated period relative risks (RRs) for incidence of NPC were increased monotonically for males, and increased for females after 2000. The increasing trend of cohort RRs of incidence was ceased in recent birth cohorts. Both period and cohort effects of NPC mortality in China decreased monotonically. Conclusions Over the last three decades, the ASMR and crude mortality rate (CMR) of NPC has decreased, but the ASIR and crude incidence rate (CIR) increased in China. Although the potential mortality risk of NPC decreased, the risk of NPC incidence was found to increase as the period move forward, and suggested that control and prevention efforts should be enhanced.

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Section: Statistical Analysesmentioning

confidence: 99%

Incidence and mortality trends of nasopharynx cancer from 1990 to 2019 in China: an age-period-cohort analysis

Bai

Sun

et al. 2022

BMC Public Health

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“…An age-period-cohort (APC) framework was used to evaluate the effects of age, period, and cohort on disease-rate outcomes. The equation can be expressed specifically as follows (15):…”

Section: Statistical Analysesmentioning

confidence: 99%

The epidemic of thyroid cancer in China: Current trends and future prediction

Zhao

Sun

et al. 2022

Front. Oncol.

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BackgroundThyroid cancer (TC) is one of the most common cancers in China. The aim of this study was to identify the potential age, period, and cohort effect under the long-term trends in TC incidence and mortality, making projections up to 2030.MethodsIncidence and mortality data on TC were obtained from the Global Burden of Disease Study 2019. The population predictions were obtained from the United Nations World Population Prospects 2019. An age–period–cohort model was used for the analysis.ResultsFrom 1990 to 2019, the net drift (the overall annual percentage change of TC over time adjusted for age groups) of the TC incidence was 5.01% (95% confidence interval [CI]: 4.72%, 5.29%) for men and 1.48% (95% CI: 1.14%, 1.82%) for women. The net drift of TC mortality was 1.64% (95% CI: 1.38%, 1.91%) for men and –2.51% (95% CI: –2.77%, –2.26%) for women. Regarding the incidence of TC, both the period and the cohort relative risks (RRs) in men and women showed an overall increasing trend. As to the mortality rate of TC, both the period and cohort RRs in women showed a monotonic declining trend. The period RRs for men decreased after 2015, but the cohort RRs revealed a fluctuating upward pattern. From 2019 to 2030, the TC incidence was projected to rise by 32.4% in men and 13.1% in women, the mortality declining by 13.0% in men and 17.3% in women. The elderly was projected to have an increasing proportion of TC occurrence and deaths.ConclusionsOver the past 30 years, the incidence rate of TC in China has continually increased, and this trend was projected to continue. Although male mortality has increased in the past, it is expected to decline in the future. The proportion of older people among TC occurrence and death was projected to gradually increase, and the difficulties elderly with TC lrequire more attention.

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“…Schizophrenia is a challenging mental health condition that has a notable impact on global public health, accounting for about 1% of total disability-adjusted life years (Mohammed et al, 2022;Dong et al, 2022).…”

Section: Introductionmentioning

confidence: 99%

The Ulnar Left Second Digital Ridge Count Poorly Predicts the Risk for Schizophrenia

Ibrahim,

Umar,

Andujeh

et al. 2024

Preprint

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Background Anthropometric measurements, reflecting the interplay of nutritional, environmental, and genetic factors, are commonly used to study human physical traits. Despite previous research suggesting their potential as indicators of neurodevelopmental processes and genetic influences, their role in predicting schizophrenia risk remains uncertain. This study aims to address this gap by investigating the predictive value of the ulnar left second digital ridge count in assessing the risk for schizophrenia, contributing to our understanding of the association between anthropometric variables and schizophrenia risk. Method Digit lengths were measured from the basal crease of the digit to the fingertip using a digital sliding caliper (MicroMak, USA). A digital scanner (Digital Persona, China) was utilized to capture the fingerprint pattern. Ridge count was determined by counting the ridges diagonally within a 5 mm × 5 mm area on the fingertip surface, located on the radial and ulnar sides of the distal regions of each finger. Results The proportion of the loop fingerprint pattern (ulnar and radial) on the left fourth finger of schizophrenia patients was significantly higher than that observed among the healthy volunteers. Generally, a smaller 2D:4D ratio was observed among male schizophrenia patients compared to female schizophrenia patients. The ridge counts in the second and fourth digits were significantly different among the patients compared to the healthy volunteers, except for the radial ridge counts on the left second digit. Conclusion Despite the varying degrees of association observed between the assessed anthropometric variables and schizophrenia risk, the diagnostic performance of each variable, as evaluated through ROC curve analysis, was consistently poor. Overall, these findings suggest that the sensitivity and specificity of these measurements in effectively distinguishing the disease remain inadequate. Further research is warranted to explore additional predictive factors and improve diagnostic accuracy in schizophrenia risk assessment.

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Temporal Trends in the Incidence and Disability Adjusted Life Years of Schizophrenia in China Over 30 Years

Cited by 13 publications

References 41 publications

Incidence and mortality trends of nasopharynx cancer from 1990 to 2019 in China: an age-period-cohort analysis

Incidence and mortality trends of nasopharynx cancer from 1990 to 2019 in China: an age-period-cohort analysis

The epidemic of thyroid cancer in China: Current trends and future prediction

The Ulnar Left Second Digital Ridge Count Poorly Predicts the Risk for Schizophrenia

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