Temporal requirements of associative short-term potentiation in CA1 neurons of rat hippocampus

Auyeung, Ariana; May, P. B. Y.; Goh, Joanne W.; Sastry, B.R.

doi:10.1016/0304-3940(87)90682-3

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1994

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“…The essence of the associative LTP methodology is the following: High-frequency stimulation of one input with low-intensity (weak) current is ineffective in inducing LTP. However, if the weak input is stimulated at the same time as a second strong input, then LTP will occur at the weak input (Auyeung, May, Goh, & Sastry, 1987;Brown, Kairiss, & Keenan, 1990;Sastry, Goh, & Auyeung, 1986). The dependence of the development of LTP on the necessary pairing of two (weak and strong) inputs led to the conception ofLTP as an associative process (Levy & Steward, 1979).…”

Section: Definition Of Termsmentioning

confidence: 99%