Temporal relationship of allergic rhinitis with asthma and other co-morbidities in a Mediterranean country: A retrospective study in a tertiary reference allergy clinic

Makris, Michael; Koulouris, S.; Koti, I.; Aggelides, Xenophon; Sideri, Kyriaki; Chliva, Caterina; Vassilatou, Evangeline; Kalogeromitros, D.

doi:10.1016/j.aller.2009.11.007

Cited by 14 publications

(8 citation statements)

References 13 publications

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“…Therefore, standardised pollen tablets are recommended . Moreover, allergic reactions including anaphylaxis have been recognised after intake of bee‐collected pollen . Accordingly, patients who are prone to allergies or atopic individuals should avoid any type of bee pollen, both bee‐collected and extracts.…”

Section: Bee Pollenmentioning

confidence: 99%

Biological and therapeutic properties of bee pollen: a review

2016

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Natural products, including bee products, are particularly appreciated by consumers and are used for therapeutic purposes as alternative drugs. However, it is not known whether treatments with bee products are safe and how to minimise the health risks of such products. Among others, bee pollen is a natural honeybee product promoted as a valuable source of nourishing substances and energy. The health-enhancing value of bee pollen is expected due to the wide range of secondary plant metabolites (tocopherol, niacin, thiamine, biotin and folic acid, polyphenols, carotenoid pigments, phytosterols), besides enzymes and co-enzymes, contained in bee pollen. The promising reports on the antioxidant, anti-inflammatory, anticariogenic antibacterial, antifungicidal, hepatoprotective, anti-atherosclerotic, immune enhancing potential require long-term and large cohort clinical studies. The main difficulty in the application of bee pollen in modern phytomedicine is related to the wide species-specific variation in its composition. Therefore, the variations may differently contribute to bee-pollen properties and biological activity and thus in therapeutic effects. In principle, we can unequivocally recommend bee pollen as a valuable dietary supplement. Although the bee-pollen components have potential bioactive and therapeutic properties, extensive research is required before bee pollen can be used in therapy. © 2016 Society of Chemical Industry.

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Section: Bee Pollenmentioning

confidence: 99%

Biological and therapeutic properties of bee pollen: a review

2016

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“…It includes allergic rhinitis, allergic conjunctivitis, allergic bronchial asthma, and less frequently, urticaria [1]. Seasonal allergies are often characterized by the recurrence of symptoms which show periods of improvement and relapse [2]. The allergic manifestations are more prevalent during the plant pollination season; hence, accurate descriptions of its start and end periods are important for both patients and clinicians alike [3,4,5].…”

Section: Introductionmentioning

confidence: 99%

Seasonal variations of allergenic pollen in a Mediterranean region – Alexandroupolis, north-east Greece

Nikolaidis¹,

Katotomichelakis²,

Nena³

et al. 2015

Ann Agric Environ Med.

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Objectives. The aim of this study was to describe the aerobiological characteristics of NE Greece, identify the most prevalent taxa, define the duration of the main pollen season and correlate allergen records with meteorological parameters. Materials and method. A 7-day volumetric trap, running continuously throughout the year, was used to collect circulating pollen. Pollen taxa were characterized by standard protocols and counted as grains/m 3 . The main pollen season was deduced from these data and running means (10-day averages) were plotted against time. Correlations with climatic factors (temperature, rain, humidity, wind velocity) were assessed by single linear regression analysis. Results. In total, 11 pollen families were identified, including 6 arboreal and 5 non-arboreal taxa. The 5 most prevalent taxa were Oleaceae, Fagaceae, Poaceae, Cupressaceae and Pinaceae. Peak pollen concentrations were detected in April and May, with daily averages exceeding 410 grains/m 3 . Compositeae had the longest pollen season of 135 days and Oleaceae the shortest, extending to only 27 days. Correlations with meteorological parameters showed variable associations among different taxa, with mean temperature (p<0.001), relative humidity (p=0.015), and wind speed (p=0.042) emerging as the most significant determinants as regards total pollen counts. Conclusions. Describing the aerobiological characteristics of NE Greece enabled the identification of allergenic risks that are specific for this region. Records generated in this study can be used to alert sensitized individuals of prevailing seasonal patterns, in order to take necessary precautions against imminent exposures. The monitoring system established here can serve as a reference guide for future epidemiological research focusing on allergic asthma and rhinitis.

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“…Previous findings about the sequence of onset of rhinitis and asthma show that when both diseases occur within one patient this is likely to happen within one year [ 16 , 17 ]. Supporting these findings, in this study patients with both diseases represent a relevant group (14%) and the share of rhinitis and asthma patients reporting an additional diagnosis over the observation period is small (AR 12%, AA 28%).…”

Section: Discussionmentioning

confidence: 99%

Course of respiratory allergy by treatment strategy based on German routine data

et al. 2017

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PurposeAllergic respiratory diseases represent a global health problem. The two major treatment strategies are symptom treatment and specific immunotherapy (SIT). SIT is considered the only causal treatment option available with the ability to alter the course of the disease. This study aims to describe the course of disease and medication of respiratory allergy across treatment strategies and disease groups.MethodsThe analysis is based on routine data from a German statutory health insurance. The patient cohort is observed from 2007–2012. For each year based on assured outpatient diagnoses patients are assigned to a disease group: rhinitis, asthma or both diseases. Additionally, prescribed medication is considered. Treatment comparisons are based on matched pairs.ResultsThe study population comprises 165,446 patients with respiratory allergy. In 2007 the most frequent disease group is rhinitis (70%), followed by asthma (16%) and both diseases (14%). During the observation period a second allergic respiratory diagnosis occurs only in about 12% of rhinitis patients and 28% of asthma patients. In about 50% of patients with both diseases one of the diagnoses is omitted. These patients are more likely to no longer report their asthma diagnosis when receiving immunotherapy compared to symptom treatment. Furthermore immunotherapy reduces the frequency of asthma medication use.ConclusionsResults of detailed analysis of diagnoses reflect the alternating nature of allergic diseases. Although limited by accuracy of documentation and the lack of clinical information, the comparison of treatment strategies shows some advantages of immunotherapy regarding course of disease and asthma medication use.

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Temporal relationship of allergic rhinitis with asthma and other co-morbidities in a Mediterranean country: A retrospective study in a tertiary reference allergy clinic

Abstract: The unique environmental conditions and the aerobiology of each area clearly affect the clinical features of respiratory allergy.

Cited by 14 publications

References 13 publications

Biological and therapeutic properties of bee pollen: a review

Biological and therapeutic properties of bee pollen: a review

Seasonal variations of allergenic pollen in a Mediterranean region – Alexandroupolis, north-east Greece

Course of respiratory allergy by treatment strategy based on German routine data

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