Abstract:24Macrophages are the first-line host defense where the invading Mycobacterium 25 tuberculosis (Mtb) encounters. It has been recently reported that host aerobic glycolysis 26 was elevated post the infection by a couple of virulent mycobacterial species. However, 27 whether this metabolic transition is required for host defense against intracellular 28 pathogens and the underlying mechanisms remain to be further investigated. By 29 analyzing carbon metabolism, we found that macrophages infected by M. marinum… Show more
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