2007
DOI: 10.1523/jneurosci.0426-07.2007
|View full text |Cite
|
Sign up to set email alerts
|

Temporal Dissociation between Hand Shaping and Grip Force Scaling in the Anterior Intraparietal Area

Abstract: In humans, both clinical and functional imaging studies have evidenced the critical role played by the posterior parietal cortex, and particularly by the anterior intraparietal area (AIP), in skilled hand movements. However, the exact contribution of AIP to precision grasping remains debated. Here we used transcranial magnetic stimulation (TMS) to induce virtual lesions of the left and/or right AIP in subjects performing a grip-lift task with either hand. We found that, during movement preparation, a virtual l… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1
1

Citation Types

15
126
3

Year Published

2008
2008
2023
2023

Publication Types

Select...
4
3

Relationship

0
7

Authors

Journals

citations
Cited by 129 publications
(147 citation statements)
references
References 48 publications
15
126
3
Order By: Relevance
“…2, Table 1), allowed us to isolate brain areas involved in movement generation and then examine with MVPA the preparatory activity (plan phase) that forms between the two trial phases (note that the [execute Ͼ preview] contrast also allowed us to even localize movement-related areas containing baseline activity levels during planning and yet still examine whether predictive movement information is represented in the corresponding spatial voxel patterns). Within this network, we focused MVPA on 11 commonly described neuroanatomical ROIs in both the left and right hemispheres (22 ROIs total), each examined in our previous studies (Gallivan et al, 2011a,b) and each previously implicated in visuomotor processing in both the human and monkey: (1) superior parieto-occipital cortex (SPOC), a general region thought to be involved in reach preparation and execution Prado et al, 2005;Cavina-Pratesi et al, 2010); (2) posterior intraparietal sulcus (pIPS), a general area involved in attention and hand movement-related processes (Calton et al, 2002;Beurze et al, 2009;Chang and Snyder, 2010;Szczepanski et al, 2010); (3) middle IPS (midIPS), an area involved in limb movements Gallivan et al, 2011a,b); (4) anterior IPS (aIPS), a region involved in hand grasping Frey et al, 2005;Tunik et al, 2005;Davare et al, 2007a); (5) an area posterior to anterior IPS (post. aIPS), an area involved in object-related processing and hand preshaping (Valyear et al, 2007;Gallivan et al, 2011b); (6) motor cortex, a region predominantly involved in contralateral limb movement (Tanji et al, 1988;Kim et al, 1993;Cisek et al, 2003) and the primary source of descending projections to spinal cord (Porter and Lemon, 1993); (7) dorsal premotor cortex (PMd), a region primarily involved in reach-related processes (Caminiti et al, 1990a,b;Pesaran et al, 2006;Cavina-Pratesi et al, 2010), although also implicated in grasping (Raos et al, 2004;Cavina-Pratesi et al, 2010); (8) ventral premotor (PMv) cortex, an ROI most often implicated in hand-related actions Graziano et al, 1994;Cavina-Pratesi et al, 2010;Davare et al, 2010); (9) supplementary motor area (SMA) and (10) preSMA, two medial frontal areas involved in internally generated actions and sequencing together limb movements (Kermadi et al, 1997;…”
Section: Methodsmentioning
confidence: 99%
See 3 more Smart Citations
“…2, Table 1), allowed us to isolate brain areas involved in movement generation and then examine with MVPA the preparatory activity (plan phase) that forms between the two trial phases (note that the [execute Ͼ preview] contrast also allowed us to even localize movement-related areas containing baseline activity levels during planning and yet still examine whether predictive movement information is represented in the corresponding spatial voxel patterns). Within this network, we focused MVPA on 11 commonly described neuroanatomical ROIs in both the left and right hemispheres (22 ROIs total), each examined in our previous studies (Gallivan et al, 2011a,b) and each previously implicated in visuomotor processing in both the human and monkey: (1) superior parieto-occipital cortex (SPOC), a general region thought to be involved in reach preparation and execution Prado et al, 2005;Cavina-Pratesi et al, 2010); (2) posterior intraparietal sulcus (pIPS), a general area involved in attention and hand movement-related processes (Calton et al, 2002;Beurze et al, 2009;Chang and Snyder, 2010;Szczepanski et al, 2010); (3) middle IPS (midIPS), an area involved in limb movements Gallivan et al, 2011a,b); (4) anterior IPS (aIPS), a region involved in hand grasping Frey et al, 2005;Tunik et al, 2005;Davare et al, 2007a); (5) an area posterior to anterior IPS (post. aIPS), an area involved in object-related processing and hand preshaping (Valyear et al, 2007;Gallivan et al, 2011b); (6) motor cortex, a region predominantly involved in contralateral limb movement (Tanji et al, 1988;Kim et al, 1993;Cisek et al, 2003) and the primary source of descending projections to spinal cord (Porter and Lemon, 1993); (7) dorsal premotor cortex (PMd), a region primarily involved in reach-related processes (Caminiti et al, 1990a,b;Pesaran et al, 2006;Cavina-Pratesi et al, 2010), although also implicated in grasping (Raos et al, 2004;Cavina-Pratesi et al, 2010); (8) ventral premotor (PMv) cortex, an ROI most often implicated in hand-related actions Graziano et al, 1994;Cavina-Pratesi et al, 2010;Davare et al, 2010); (9) supplementary motor area (SMA) and (10) preSMA, two medial frontal areas involved in internally generated actions and sequencing together limb movements (Kermadi et al, 1997;…”
Section: Methodsmentioning
confidence: 99%
“…stimulation studies in monkeys (Aizawa et al, 1990;Boudrias et al, 2010) and rodents (Brus-Ramer et al, 2009), as well as TMS studies in humans (Chen et al, 1997;Stedman et al, 1998;Tinazzi and Zanette, 1998;Foltys et al, 2001;Davare et al, 2007b), all suggest a role for ipsilateral motor cortex in limb movements. However, what remains vague across many of these studies is the specific role/function of these ipsilateral representations.…”
Section: Decoding In the Motor And Sensory Corticesmentioning
confidence: 99%
See 2 more Smart Citations
“…Moreover, M1 also seems to play a crucial role in storing previously acquired information about the load since a virtual lesion of M1 induced by repeated TMS disrupted the scaling of the grip forces based on information acquired during a previous lift ( [8]; see [34]). Similarly timed TMS of other cortical areas principally disrupted the timing of the lift phase in the case of the dorsal premotor cortex or the positioning of the fingertips in the case of the ventral premotor and parietal cortex [10,11].…”
Section: Introductionmentioning
confidence: 99%